Abstract
Milky spots (MS), considered by the authors as a Coelomatic Lympho-myelopoietic Organ (CLMO), present a strong reactivity during experimental schistosomal mansoni infection, characterized by an increase of lymphocytes, macrophages, plasmocytes, mast cells, neutrophils and expression of eosinophil metaplasia. Intraperitoneal injection of purified Schistosoma mansoni (Sm) eggs provoked a rise in the number and size of MS, which developed the sessile marginal and pedunculated types. The authors conclude that egg antigens are, at least partially, responsible for MS reactivity during Sm infection.
milky spot; Schistosoma mansoni; eosinophil; peritoneum
Milky spots reactions to schistosomal mansoni infection
H. L. Lenzi
D. N. Oliveira1
R. Borojevic2
J. A. Lenzi1
Instituto Oswaldo Cruz, Departamento de Patologia, Rio de Janeiro, Brasil
Universidade Federal do Rio de Janeiro, Instituto de Química, Departamento de Bioquímica, Rio de Janeiro, Brasil
Milky spots (MS), considered by the authors as a Coelomatic Lympho-myelopoietic Organ (CLMO), present a strong reactivity during experimental schistosomal mansoni infection, characterized by an increase of lymphocytes, macrophages, plasmocytes, mast cells, neutrophils and expression of eosinophil metaplasia. Intraperitoneal injection of purified Schistosoma mansoni (Sm) eggs provoked a rise in the number and size of MS, which developed the sessile marginal and pedunculated types. The authors conclude that egg antigens are, at least partially, responsible for MS reactivity during Sm infection.
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Publication Dates
-
Publication in this collection
04 June 2009 -
Date of issue
1992
