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Arquivo Brasileiro de Medicina Veterinária e Zootecnia

Print version ISSN 0102-0935

Abstract

BRUNELLI, A.T.J. et al. Excision of sclerocorneal limbus in dogs and resulting clinical events: study of an experimental model. Arq. Bras. Med. Vet. Zootec. [online]. 2006, vol.58, n.1, pp. 52-58. ISSN 0102-0935.  doi: 10.1590/S0102-09352006000100009.

^len^aThe consequences of complete removal of the sclerocorneal limbus epithelium were evaluated, as well as the model for such, in which n-heptanol and superficial keratectomy were used. The association of n-heptanol and keratectomy allowed a complete excision of stem cells. Moreover, the destruction of these cells led to significant tectonic alterations that could be employed as a feasible model for clinical experimentation of corneal transplantation.^lpt^aAs conseqüências da completa remoção do epitélio do limbo esclerocorneano foram avaliadas, bem como o modelo utilizado para tal, em que se empregou o n-heptanol e a ceratectomia superficial. O n-heptanol e a ceratectomia associados possibilitaram a completa excisão das células-tronco. Da destruição dessas células decorrem alterações tectônicas significativas factíveis para estudos dos transplantes de córnea.

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