SciELO - Scientific Electronic Library Online

 
vol.20 issue2Chemical composition and acetylcholinesterase inhibitory activity of essential oils of Myrceugenia myrcioides(Cambess.) O. Berg and Eugenia riedelianaO. Berg, MyrtaceaeInvestigation of antihyperglycemic activity of Passiflora edulis Sims, Passifloraceae, in alloxan-induced diabetic rats author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Revista Brasileira de Farmacognosia

Print version ISSN 0102-695X

Abstract

PAULA-ZURRON, Ana Claudia B. De et al. Antinociceptive activity of Ipomoea imperati (Vahl) Griseb., Convolvulaceae. Rev. bras. farmacogn. [online]. 2010, vol.20, n.2, pp.180-185. ISSN 0102-695X.  http://dx.doi.org/10.1590/S0102-695X2010000200008.

Ipomoea imperati (Vahl) Griseb., Convolvulaceae, is used in folk medicine for the treatment of inflammation, swelling and wounds, as well as to treat pains after childbirth and for stomach problems. Administration of ethanol extract, lipid and aqueous fraction of I. imperati(300, 100 and 200 mg/kg) significantly inhibited the abdominal constriction in mice induced by acetic acid; increased the sleeping time evoked by pentobarbital sodium and showed a significant activity by inhibiting formalin-induced paw edema in mice. The same dose of I. imperatialso raised the pain of mice in the hot-plate test and increased the latency at all observation times. The pre-treatment of the animals with naloxone (5 mg/kg, i.p.) suggested the participation of the opioid system in the antinociceptive effect of Ipomoea imperati.

Keywords : Ipomoea imperati; Convolvulaceae; pain; analgesic activity; opioid system.

        · abstract in Portuguese     · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License