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Education program on genetic syndromes: motivational evaluation of an e-learning material

Abstracts

Purpose

: to evaluate the motivational aspects of an material e-learning known as Cybertutor on genetic syndromes for elementary school students.

Methods

: 21 students of the 9 th grade in the city of Bauru participated in the study. After 30 days of access Cybertutor, was used a Web Site Motivational Analysis Checklist adapted (FPM) to assess motivational aspects of this tool. The questionnaire is composed of 32 statements grouped into four domains: stimulating, meaningful, organized and easy-to-use.

Results

: all participants evaluated positively material e-learning developed, considering it as “impressive.” The Friedman Test found statistically significant differences between the domains, with p = 0.002239. The comparison between the individual domains, shows significant results in the scoring area organized.

Conclusion

: Cybertutor on genetic syndromes developed received high motivational satisfaction. Thus, we conclude that this material e-learning can be used as a strategy of health education on this theme.

Health Education; Education, Distance; Motivation; Genetics


Objetivo

: avaliar os aspectos motivacionais de um material educacional on line conhecido como Cybertutor contendo informações sobre síndromes genéticas para alunos do ensino fundamental.

Métodos

: participaram deste estudo 21 alunos do 9° ano do ensino fundamental do município de Bauru. Após 30 dias de acesso ao Cybertutor, utilizou-se a Ficha de Pesquisa Motivacional para avaliar os aspectos motivacionais desta ferramenta. A Ficha de Pesquisa Motivacional é composta por 32 enunciados agrupados em 4 domínios: estimulante, significativo, organizado e fácil de usar.

Resultados

: todos os participantes avaliaram positivamente o material educacional on line desenvolvido, considerando-o como “Impressionante”. O Teste de Friedman encontrou diferença estatística significante entre os domínios avaliados, com p=0,002239. A comparação individual entre os domínios demonstra resultados significantes na pontuação do domínio organizado.

Conclusão

: o Cybertutor sobre síndromes genéticas desenvolvido obteve alta satisfação motivacional. Dessa forma, conclui-se que este material educacional on line pode ser utilizado como uma estratégia de educação em saúde nesta temática.

Educação em Saúde; Educação a Distancia; Motivação; Genética


INTRODUCTION

In Brazil, a country with approximately 190 million inhabitants, health education addressing information on genetic syndromes is extremely necessary as the data of the DataSUS show that, from 2005 to 2008, there was a total of 11,806,180 live births, and 75,814 of these were suffering from some genetic abnormality 1. Ministério da Saúde. Departamento de Informática do SUS [homepage na internet] [acesso em 16 de maio de 2011]. Disponível em: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sinasc/cnv/nvuf.def
http://tabnet.datasus.gov.br/cgi/tabcgi....
.

This data make us reflect on educational practices involving genetic abnormalities in all perspectives, even contemplating disease prevention and health promotion. There is a lack of educational programs and health campaigns exploring the theme genetic syndromes specifically. Some preventive measures, guidance and genetic counseling, for instance, could be enough and significant to enable the reduction of such abnormalities incidence.

Health education is a set of knowledge and practice oriented for the prevention of diseases and promotion of health 2. Costa M, López E. Educación para la salud. Madrid: Pirámide; 1996. p. 25-58. . Scientific knowledge reaches people´s daily lives, and it may contribute to the incorporation of new habits and health behaviors 3. Alves VS. Um modelo de educação em saúde para o programa saúde da família: pela integralidade da atenção e reorientação do modelo assistencial. Interface – Comunic, Saude, Educ. 2005;9(16):39-52. . Health education must be a critical and transformative social practice, enabling reflection, behavior change, self-care and social wellness.

The educational prevention programs aim at an early identification of diseases, a health care awareness and a consequent decrease in treatment costs for the health systems 4. Rondon S, Chaar LJE, Silva AP, Sequeira E, Chao RS, Chao LW. Educação e promoção em saúde por meio do uso de tecnologia e ação de estudantes em suas comunidades – projeto jovem doutor. In: Anais do IV Congresso Brasileiro de Telemedicina e Telessaúde; Belo Horizonte MG. Belo Horizonte; 2009. [acesso em 10 de jan de 2011]. Disponível em: http://www.cbtms.com.br/congresso/trabalhos/063.pdf
http://www.cbtms.com.br/congresso/trabal...
. It is extremely important to invest in initiatives that strengthen health education and disease prevention in Brazil, a country with extensive geographic dimensions, and, above all, limited basic health structures. In this perspective, the modern information and communication technologies (ICTs) allow a fast dissemination of information. In this context, Distance Education (DE) becomes an important strategy to aggregate a higher number of people, minimize geographical difficulties and costs, as well as optimize the time necessary for the development of health education procedures 5. Spinardi ACP, Blasca WQ, De-Vitto LM. Genética e fonoaudiologia: aprendizado baseado na teleducação. Pró-Fono R. Atual. Cient. 2008; 20(Supl):42-4.,6. Silva ASC, Rizzante FAP, Picolini MM, Campos K, Corrêa CC, Franco EC, et al. Bauru school of dentistry tele-health league: an educational estrategy applied to research, teaching and extension among applications in tele-health. J Appl Oral Sci. 2011;19(6):599-603. .

The terms “ED” and “Tele-education” are often used as synonyms. However, Tele-education must be seen as an optimization of processes, an environment gathering technologies to increase educational efficiency of both traditional methods and distance courses 5. Spinardi ACP, Blasca WQ, De-Vitto LM. Genética e fonoaudiologia: aprendizado baseado na teleducação. Pró-Fono R. Atual. Cient. 2008; 20(Supl):42-4. .

The Interactive Tele-education gathers many technologies, such as videoconference (for real time interactions), Internet based systems (cybertutor , classroom of the future, online tutor, web conference) and learning objects (The Virtual Man Project and videos demonstrating surgical and clinical procedures) 7. Wen CL. Telemedicina - visão sob foco de uma disciplina. Rev Telem Telessaude. 2006;2(2):20-6. [acesso em 24 de maio de 2010]. Disponível em: http://www.estacaodigitalmedica.com.br/edm/institucional/publicacoes/jornal_dez2006.pdf.
http://www.estacaodigitalmedica.com.br/e...
.

The Cybertutor enables the student learning through the internet, in an interactive way, allowing both student and tutor to verify the performance. It also presents interactivity resources, such as forum and discussion list, which assures a greater proximity between the program tutor and its participants 8. Wen CL, Silveira PSP, Azevedo RS, Böhm GM. Internet discussion lists as an educational tool. J Telemed Telecare. 2000;6(5):302-4 .

Theoretical content, videos and images can be provided in this system. Besides that, it is possible to direct the students learning with the Cybertutor. After each topic studied, questions are asked and the answers are assessed immediately, offering a feedback to the user 5. Spinardi ACP, Blasca WQ, De-Vitto LM. Genética e fonoaudiologia: aprendizado baseado na teleducação. Pró-Fono R. Atual. Cient. 2008; 20(Supl):42-4. . Individual performance reports are available for tutors, so that the student work can be monitored. This study aimed at verifying the motivational aspects of an e-learning material, the Cybertutor, on genetic syndromes for 9 th grade students.

METHODS

Initially, the Department of Speech-Language Pathology and Audiology of the Bauru School of Dentistry, University of São Paulo, (FOB-USP) in a partnership with the discipline Telemedicine of the University of São Paulo (DTM/FMUSP) developed an e-learning material on genetic syndromes for elementary school students 9. Picolini MM, Blasca WQ, Richieri-Costa A, Maximino LP. A elaboração de um ambiente virtual de aprendizagem em síndromes genéticas. Rev CEFAC. 2012. No prelo. .

Entitled Cybertutor , the material was made available on the Project Young Doctor (http://www.jovemdoutor.org.br/jdr/).

In order to obtain the sample, we got in touch with the City Department of Education, located in the interior of the São Paulo state, to get a list of private and public schools. Some schools were randomly chosen to be visited and to receive the study proposal and 2 schools accepted to take part in the study.

The objective of the study was also presented to all 9th grade students attending Elementary School in both schools. The 9 th grade was chosen mainly because the program theme was related to the Genetic Syndromes and the fact that these students were attending the discipline Sciences and / or Biology. The participation in the study was voluntary due to interest and availability.

In this context, 21 9 th grade students enrolled in the elementary school in Bauru, took part in the study, 4 ((19%) were male and 17 (81%) female, aged from 13 to 14 years old.

The students could access the Cybertutor in computer rooms available in the school or on their own personal computers, at home, accessing as many times as it was necessary. So, the activities were carried out in different periods of the school period. After 30 days having access to the Cybertutor on genetic syndromes, the students answered an assessment questionnaire.

To assess the Cybertutor motivational aspects as an e-learning material, a Web Site Motivational Analysis Checklist (WebMAC) Professional Adapted was used as showed in image 1.

Figure 1
– Web Site Motivational Analysis Checklist (WebMAC) Professional Adapted (Paixão, 2008)

The questionnaire used was adaptation of the tool Web Site Motivational Analysis Checklist (WebMAC) Professional 1111 . Small RV, Arnone MP. Motivation mining: prospecting the web. Book Report. 1999;18:42-4. . This tool was developed to assess websites and, after adaptation, it became applicable for the motivational subjective assessment of courses and programs involving DE.

The WebMAC consists of 32 statements. Each statement is scored numerically as follows: (3) strongly agree, (2) somewhat agree, (3) somewhat disagree, (0) strongly disagree.

These statements were gathered in 4 domains: “STIMULATING”, “MEANINGFUL”, “ORGANIZED” and “EASY TO USE”. The domain “STIMULATING” consists of the statements 1, 5, 9, 13, 17, 21, 25 and 29; the domain MEANINGFUL” consists of the statements 2, 6, 10, 14, 18, 22, 26 and 30; the domain “ORGANIZED” of the 3, 7, 11, 15, 19, 23, 27 and 31 and the domain “EASY TO USE” of the statements 4, 8, 12, 16, 20, 24, 28, and 32. Each domain can reach a total of 8 statements. Thus, each domain has a maximal score of 24 points and a minimum score of 0 points.

After the score of each domain is carried out individually, they are grouped as the expression: V= E+S; XS= O+F. The score V is the sum of the domains “STIMULATING” and “MEANINGFUL” and it reflects the dimension “VALUE”, that is, how much this material is valuable. The score XS is the sum of the domains “ORGANIZED” and “EASY TO USE” and it reflects the dimension “Expectation for Success”.

To finish the score, the authors of the WebMAC recommend the use of a Cartesian projection. The abscissa (x-axis) is the score corresponding to the dimension “Value” and the ordinate (y-axis) is the score corresponding to the dimension “Expectation for Success”. If the points or a high amount of individual points be located inside the area in grey, it means that the Cybertutor, as an e-learning material, is an “Impressive course”, being positively assessed (Image 2).

Figure 2
– Criteria of classification based on the WebMAC Professional

Previously to the study, the persons in charge of the students were properly informed on its objectives and procedures. Besides, the ones who agreed with their children taking part in the study were asked to sign an Informed Consent Form (ICF). This study was approved by the Research Ethics Committee of the FOB/USP, under the protocol number 039/2009.

Data analysis consisted of a descriptive analysis using the ranges maximum and minimum, mean and median. The Friedman test was used for the comparative analysis of the domains, considering a level of significance of 5% (p≤0.05).

RESULTS

The WebMAC was answered by all the students (100%) who accessed the Cybertutor (Image 3). The students took 15 minutes in average to answer it.

Figure 3
– Score obtained by student in each assessed domain of the WebMAC

The domain with the highest mean according to the students was the “ORGANIZED”, receiving a significant number of positive assessments (strongly agree and somewhat agree”). The domain with the lowest mean was the “EASY TO USE”, receiving a significant number of negative assessments (“strongly disagree and somewhat disagree”) (Table 1).

Table 1
– Values of mean, median, minimum, maximum and standard deviation (SD) for assessed domain of the WebMAC.

The Friedman Test was used to compare the domains assessed by the WebMAC, and it found a statistically significant difference with p=0.002239 (Table 2). Thus, considering the four domains, the individual comparison for the Friedman Test was applied, and it verified a significant difference comparing the domain “ORGANIZED” with the others (Table 3).

Table 2
– Comparison of the assessed domains by the WebMAC
Table 3
- Individual comparison of the domains for the Friedman Test

The level of motivational satisfaction verified for the e-learning material developed was “impressive”, indicating a positive assessment for 100 % of the sample (Image 4).

Figure 4
– Classification of the Cybertutor, as an e-learning material

DISCUSSION

Some studies 4. Rondon S, Chaar LJE, Silva AP, Sequeira E, Chao RS, Chao LW. Educação e promoção em saúde por meio do uso de tecnologia e ação de estudantes em suas comunidades – projeto jovem doutor. In: Anais do IV Congresso Brasileiro de Telemedicina e Telessaúde; Belo Horizonte MG. Belo Horizonte; 2009. [acesso em 10 de jan de 2011]. Disponível em: http://www.cbtms.com.br/congresso/trabalhos/063.pdf
http://www.cbtms.com.br/congresso/trabal...
, 1212 . Macéa DD, Rondon S, Chaar LJ, Wen CL. Public health education for young students aided by technology. J Telemed Telecare. 2009;15(3):159.

13 . Picolini MM, Campos K, Oliveira JRM, Maximino LP, Blasca WQ. Prevenção e promoção da saúde auditiva: o projeto jovem doutor na formação de agentes multiplicadores. In: Anais do IV Seminário científico de políticas públicas, serviços e sistemas em saúde auditiva; Bauru SP. Bauru; 2010.
-1414 . Toassa EC, Leal GVS, Wen CL, Philippi ST. Atividades lúdicas na orientação nutricional de adolescents do Projeto Jovem Doutor. Rev Soc Bras Alim Nutr. 2010;35(3):17-27. show that the early incorporation of healthy habits can generate a change in the behavior; therefore, it must be encouraged by educational programs developed for children and adolescents.

As 100% of the sample consisted of adolescents, aged between 13 and 14 years old, there was a preoccupation in adopting an appropriate language and an engaging learning content.

The learning material developed was a Cybertutor on genetic syndromes. As it is an electronic tutor available on the internet, the time of access was flexible, according to the time availability and interest of the students.

Nowadays, a variety of studies are being developed aiming at assessing the effectiveness 1515 . Blasca WQ, Maximino LP, Galdino DG, Campos K, Picolini MM. Novas tecnologias educacionais no ensino da Audiologia. Rev CEFAC. 2010;12(6)1017-24. , acceptance 1616 . Melo TM, Alvarenga KF, Blasca WQ, Taga MFL. Opinião dos agentes comunitários de saúde sobre o uso da videoconferência na capacitação em saúde auditiva infantil. Rev CEFAC. 2011;13(4):692-7. and motivation 1717 . Paixão MP, Miot HA, Wen CL. Tele-education on leprosy: evaluation of an educational strategy. Telemed J E Health. 2009;15(6):552-9. of the users regarding distance education.

The domain “ORGANIZED” was the one with the highest score in the sample (Table 1). The organization of the learning material is an extremely important variable, as the planning, the development and the information layout are determining prerequisites that can influence in the users motivation, in the learning and consequently in the effectiveness of the education program.

Regarding the domain with the lowest score “EASY TO USE” (Table 3), this data enables us to conclude that distance education programs can still be considered an innovative education practice, mainly for this study age group.

According to Image 2, the results showed a high level of motivational satisfaction with the e-learning material developed. Other studies 1717 . Paixão MP, Miot HA, Wen CL. Tele-education on leprosy: evaluation of an educational strategy. Telemed J E Health. 2009;15(6):552-9.,1818 . Paixão MP, Miot HA, Souza PE, Haddad AE, Wen CL. A university extension course in leprosy: telemedicine in the Amazon for primary healthcare. J Telemed Telecare. 2009;15(2):64-7. have also verified that the MRF is a high valid tool to measure the motivational aspecto of distance courses.

This positive assessment regarding the Cybertutor as an e-learning interactive material corroborates with the literature checked 4. Rondon S, Chaar LJE, Silva AP, Sequeira E, Chao RS, Chao LW. Educação e promoção em saúde por meio do uso de tecnologia e ação de estudantes em suas comunidades – projeto jovem doutor. In: Anais do IV Congresso Brasileiro de Telemedicina e Telessaúde; Belo Horizonte MG. Belo Horizonte; 2009. [acesso em 10 de jan de 2011]. Disponível em: http://www.cbtms.com.br/congresso/trabalhos/063.pdf
http://www.cbtms.com.br/congresso/trabal...
,1010 . Paixão MP. Modelo de educação a distância em hanseníase voltado para a rede de detecção de casos e diagnóstico [tese]. São Paulo: Faculdade de Medicina, Universidade de São Paulo; 2008.,1212 . Macéa DD, Rondon S, Chaar LJ, Wen CL. Public health education for young students aided by technology. J Telemed Telecare. 2009;15(3):159.,1313 . Picolini MM, Campos K, Oliveira JRM, Maximino LP, Blasca WQ. Prevenção e promoção da saúde auditiva: o projeto jovem doutor na formação de agentes multiplicadores. In: Anais do IV Seminário científico de políticas públicas, serviços e sistemas em saúde auditiva; Bauru SP. Bauru; 2010.,1515 . Blasca WQ, Maximino LP, Galdino DG, Campos K, Picolini MM. Novas tecnologias educacionais no ensino da Audiologia. Rev CEFAC. 2010;12(6)1017-24.,1717 . Paixão MP, Miot HA, Wen CL. Tele-education on leprosy: evaluation of an educational strategy. Telemed J E Health. 2009;15(6):552-9.

18 . Paixão MP, Miot HA, Souza PE, Haddad AE, Wen CL. A university extension course in leprosy: telemedicine in the Amazon for primary healthcare. J Telemed Telecare. 2009;15(2):64-7.

19 . Eskenazi ES, Martins MA, Ferreira MJr. Oral health promotion through an online training program for medical students. J Dent Educ. 2011;75(5):672-8.
-2020 . Soirefmann M, Boza JC, Comparin C, Cestari TF, Wen CL. Cybertutor: um objeto de ensino na Dermatologia. Na. Bras. Dermatol. [periódico na Internet]. 2010;85(3):400-2. . Thus, if an e-learning material has a high motivational quality, the users visit, explore the content and access again 1717 . Paixão MP, Miot HA, Wen CL. Tele-education on leprosy: evaluation of an educational strategy. Telemed J E Health. 2009;15(6):552-9. .

The high motivational satisfaction was also verified in a study 2121 . Carvalho, José Luiz Brito de. Promoção da saúde em ensino fundamental: ações de teleducação em Fonoaudiologia na inclusão escolar [dissertação]. Bauru: Universidade de São Paulo, Faculdade de Odontologia de Bauru; 2012 [acesso 2012-12-12]. Disponível em: http://www.teses.usp.br/teses/disponiveis/25/25143/tde-01112012-173439/.
http://www.teses.usp.br/teses/disponivei...
on the theme genetic syndromes, demonstrating similar findings in the assessment of e-learning materials carried out by students who live in the state of Amazonas.

In this perspective, the results found in this study show that the development of health education programs must be encouraged by education practices, including those using the Interactive Tele-education.

CONCLUSION

Considering the data obtained, it was possible to conclude that the Cybertutor on genetic syndromes received a high motivational satisfaction among the elementary school students, and it can be used in health education programs on this theme for this age population.

ACKNOWLEDGMENTS

To the São Paulo Research Foundation (FAPESP) for the support given in our research, under the process number 2009/03362-5. To the FMUSP Telemedicie team, especially to Professor Dr. Chao Lung Wen, who made this study possible to be done.

REFERÊNCIAS

  • 1
    Ministério da Saúde. Departamento de Informática do SUS [homepage na internet] [acesso em 16 de maio de 2011]. Disponível em: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sinasc/cnv/nvuf.def
    » http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sinasc/cnv/nvuf.def
  • 2
    Costa M, López E. Educación para la salud. Madrid: Pirámide; 1996. p. 25-58.
  • 3
    Alves VS. Um modelo de educação em saúde para o programa saúde da família: pela integralidade da atenção e reorientação do modelo assistencial. Interface – Comunic, Saude, Educ. 2005;9(16):39-52.
  • 4
    Rondon S, Chaar LJE, Silva AP, Sequeira E, Chao RS, Chao LW. Educação e promoção em saúde por meio do uso de tecnologia e ação de estudantes em suas comunidades – projeto jovem doutor. In: Anais do IV Congresso Brasileiro de Telemedicina e Telessaúde; Belo Horizonte MG. Belo Horizonte; 2009. [acesso em 10 de jan de 2011]. Disponível em: http://www.cbtms.com.br/congresso/trabalhos/063.pdf
    » http://www.cbtms.com.br/congresso/trabalhos/063.pdf
  • 5
    Spinardi ACP, Blasca WQ, De-Vitto LM. Genética e fonoaudiologia: aprendizado baseado na teleducação. Pró-Fono R. Atual. Cient. 2008; 20(Supl):42-4.
  • 6
    Silva ASC, Rizzante FAP, Picolini MM, Campos K, Corrêa CC, Franco EC, et al. Bauru school of dentistry tele-health league: an educational estrategy applied to research, teaching and extension among applications in tele-health. J Appl Oral Sci. 2011;19(6):599-603.
  • 7
    Wen CL. Telemedicina - visão sob foco de uma disciplina. Rev Telem Telessaude. 2006;2(2):20-6. [acesso em 24 de maio de 2010]. Disponível em: http://www.estacaodigitalmedica.com.br/edm/institucional/publicacoes/jornal_dez2006.pdf.
    » http://www.estacaodigitalmedica.com.br/edm/institucional/publicacoes/jornal_dez2006.pdf
  • 8
    Wen CL, Silveira PSP, Azevedo RS, Böhm GM. Internet discussion lists as an educational tool. J Telemed Telecare. 2000;6(5):302-4
  • 9
    Picolini MM, Blasca WQ, Richieri-Costa A, Maximino LP. A elaboração de um ambiente virtual de aprendizagem em síndromes genéticas. Rev CEFAC. 2012. No prelo.
  • 10
    Paixão MP. Modelo de educação a distância em hanseníase voltado para a rede de detecção de casos e diagnóstico [tese]. São Paulo: Faculdade de Medicina, Universidade de São Paulo; 2008.
  • 11
    Small RV, Arnone MP. Motivation mining: prospecting the web. Book Report. 1999;18:42-4.
  • 12
    Macéa DD, Rondon S, Chaar LJ, Wen CL. Public health education for young students aided by technology. J Telemed Telecare. 2009;15(3):159.
  • 13
    Picolini MM, Campos K, Oliveira JRM, Maximino LP, Blasca WQ. Prevenção e promoção da saúde auditiva: o projeto jovem doutor na formação de agentes multiplicadores. In: Anais do IV Seminário científico de políticas públicas, serviços e sistemas em saúde auditiva; Bauru SP. Bauru; 2010.
  • 14
    Toassa EC, Leal GVS, Wen CL, Philippi ST. Atividades lúdicas na orientação nutricional de adolescents do Projeto Jovem Doutor. Rev Soc Bras Alim Nutr. 2010;35(3):17-27.
  • 15
    Blasca WQ, Maximino LP, Galdino DG, Campos K, Picolini MM. Novas tecnologias educacionais no ensino da Audiologia. Rev CEFAC. 2010;12(6)1017-24.
  • 16
    Melo TM, Alvarenga KF, Blasca WQ, Taga MFL. Opinião dos agentes comunitários de saúde sobre o uso da videoconferência na capacitação em saúde auditiva infantil. Rev CEFAC. 2011;13(4):692-7.
  • 17
    Paixão MP, Miot HA, Wen CL. Tele-education on leprosy: evaluation of an educational strategy. Telemed J E Health. 2009;15(6):552-9.
  • 18
    Paixão MP, Miot HA, Souza PE, Haddad AE, Wen CL. A university extension course in leprosy: telemedicine in the Amazon for primary healthcare. J Telemed Telecare. 2009;15(2):64-7.
  • 19
    Eskenazi ES, Martins MA, Ferreira MJr. Oral health promotion through an online training program for medical students. J Dent Educ. 2011;75(5):672-8.
  • 20
    Soirefmann M, Boza JC, Comparin C, Cestari TF, Wen CL. Cybertutor: um objeto de ensino na Dermatologia. Na. Bras. Dermatol. [periódico na Internet]. 2010;85(3):400-2.
  • 21
    Carvalho, José Luiz Brito de. Promoção da saúde em ensino fundamental: ações de teleducação em Fonoaudiologia na inclusão escolar [dissertação]. Bauru: Universidade de São Paulo, Faculdade de Odontologia de Bauru; 2012 [acesso 2012-12-12]. Disponível em: http://www.teses.usp.br/teses/disponiveis/25/25143/tde-01112012-173439/.
    » http://www.teses.usp.br/teses/disponiveis/25/25143/tde-01112012-173439/
  • Institutional Support: São Paulo Research Foundation – FAPESP.

Publication Dates

  • Publication in this collection
    Mar 2014

History

  • Received
    20 Apr 2012
  • Accepted
    10 Dec 2012
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