On-line version ISSN 2176-9451
Dental Press J. Orthod. vol.15 no.5 Maringá Sept./Oct. 2010
Letícia Guilherme FelícioI; Antônio Carlos de Oliveira RuellasII; Ana Maria BologneseIII; Eduardo Franzotti Sant'AnnaIV; Mônica Tirre de Souza AraújoIV
of Masters in Orthodontics, Faculty of Dentistry, Federal University of Rio
de Janeiro - UFRJ
IIMaster and Doctor of Orthodontics, UFRJ. Associate Professor of Orthodontics, School of Dentistry, Federal University of Rio de Janeiro - UFRJ
IIIMaster and Doctor of Orthodontics, Faculty of Dentistry, Federal University of Rio de Janeiro - UFRJ. Postdoctoral Fellow in Oral Biology - North-Western University (USA). Professor of Orthodontics, School of Dentistry, Federal University of Rio de Janeiro - UFRJ
IVMaster and Doctor of Orthodontics, Faculty of Dentistry, Federal University of Rio de Janeiro - UFRJ. Associate Professor of Orthodontics, School of Dentistry, Federal University of Rio de Janeiro - UFRJ
aim of this study was to evaluate the method for mixed-dentition analysis using
Cone-Beam Computed Tomography for assessing the diameter of intra-osseous teeth
and compare the results with those obtained by Moyers, Tanaka-Johnston, and
45-degree oblique radiographs.
METHODS: Measurements of mesial-distal diameters of erupted lower permanent incisors were made on plaster cast models by using a digital calliper, whereas assessment of the size of non-erupted permanent pre-molars and canines was performed by using Moyer's table and Tanaka-Johnston's prediction formula. For 45-degree oblique radiographs, both canines and pre-molars were measured by using the same instrument. For tomographs, the same dental units were gauged by means of Dolphin software resources.
RESULTS: Statistic analysis revealed high agreement between tomographic and radiographic methods, and low agreement between tomographs and other methods being evaluated.
CONCLUSION: Cone-Beam Computed Tomography was accurate for mixed-dentition analysis in addition to presenting some advantages over compared measurement methods: observation and measurement of intra-osseous teeth individually with the possibility, however, to view them from different prospects and without superimposition of anatomical structures.
Keywords: Mixed dentition. Cone-Beam Computed Tomography. 45-degree oblique radiograph. Plaster cast.
The majority of malocclusions involve problems related to an imbalance between the dimensions of teeth and bone base.1 However, there is a short period of dentition development in which lower arch crowding is considered acceptable. When the lower permanent lateral incisor erupts into the oral cavity, an additional space of 1.6 mm, on average, is needed to allow correct alignment of all anterior teeth.2,3 In many cases, this dental crowding is transient and tends to resolve spontaneously due to an increase in inter-canine distance, migration of deciduous canines towards primate spaces, and a more labial position of permanent incisors in relation to their deciduous antecessors.4 During this phase, it is important to analyse the mixed dentition to estimate the diameter of non-erupted permanent teeth and to assess whether dental volume is in accordance with the bone base size.
Several methods have been developed aiming for this goal, and they can be briefly grouped into three categories: Those based on regression equations, those using radiographs, and those combining these both methods.5
Among them, Moyers' analysis has been largely used because of its simplicity.6 Based on the fact that permanent teeth have highly proportional dimensions in a same individual, Moyers4 proposes a table with values for permanent canines and pre-molars not yet erupted, using as reference the diameter of permanent lower incisors.
Tanaka-Johnston's formula is a practical manner of obtaining the same information, since no table is needed. The values for pre-molars and canines of an hemi-arch are defined by adding one-half of the mesial-distal diameter of the permanent lower incisors to a pre-determined value regarding both lower and upper hemi-arches, respectively, 10.5 mm and 11.0 mm.7
Oblique radiographs at 45-degree angle have been cited as one of the most reliable methods for obtaining diameters of non-erupted teeth because it allows unilateral identification and clear visualization of posterior teeth.8-13 This method has a small magnification factor, little distortion compared to the lateral cephalometric radiograph10 and tooth size is effectively measured and not estimated.
One of the possibilities of using computed tomography in orthodontics is the exact measurement of the mesial-distal diameter of teeth for evaluation of tooth-bone discrepancies14. Three-dimensional views generated by computed tomographs allow rapid and efficient occlusion analysis, particularly in patients with mixed dentition as such images show erupted teeth as well as those erupting or developing. In addition, their relative position and root formation are also provided.15
Due to the decrease in arch length, particularly the lower one, during transition from mixed to permanent dentition, the mixed-dentition analysis is usually applied to the mandible.16
In the present study, the main objective was to compare a new method for mixed-dentition analysis, which was based on computed tomographic measurements, to those traditionally employed such as Moyers' analysis, Tanaka-Johnston prediction table and 45-degree oblique radiography.
MATERIALS AND METHODS
The sample consisted of 30 healthy patients of both genders coming from different ethnic and social backgrounds who had been enrolled in the post-graduation orthodontics program for dental treatment at the Federal University of Rio de Janeiro Dental Faculty. On clinical examination, all presented erupted permanent incisors and first molars, deciduous canines, deciduous first and second molars. These teeth had no clinically observed caries, no restorations, no loss of interproximal dental substance, no coronal fracture, and no other anomaly.
Plaster cast models were made from alginate impressions and the diameters of lower permanent incisors were obtained by using a digital calliper with precision of 0.02 mm and repetition precision of 0.01 mm (Starret, Itu, SP, Brazil). A device was made using acrylic resin and stainless steel wire and then adapted onto the tips of the digital calliper (Fig 1) to facilitate the measurement of tooth size. The maximum dental mesial-distal width was achieved by positioning the tips of calliper at the regions of contact point, parallel to occlusal or incisal surfaces and perpendicular to the tooth long axis. The values regarding the four incisors were added so that Moyers' table could be used at 75% probability level and Tanaka-Johnston's prediction formula applied, whereas the values regarding non-erupted permanent canines and pre-molars were used for prediction.
Oblique radiographs were taken at 45-degree angle during the Dental Radiology and Imaging Specialization Course at the Federal University of Rio de Janeiro (UFRJ). The radiographs of right and left sides of the same patient were taken by using an orthopantomography unit (Rotograph Plus, Villa Sistemi Midicali, Buccinasco MI, Italy). The diameters of intra-osseous teeth appearing on the 45-degree oblique radiographs were also obtained by using a digital calliper. The greatest mesial-distal width of the teeth was determined visually.
Computed tomographs performed with i-CAT scan equipment were imported under DICOM file format by using Dolphin 3D V.11 software. The measurements of both erupted tooth diameter and arch perimeter were obtained by using tools of this software. Therefore, the long axis of each tooth was corrected in the three planes-axial, coronal, and sagittal (Figs 2 and 3). The technique employed in the measurement of intra-bony teeth in this study had been previously tested to evaluate erupted teeth and was very appropriate. The method using Cone-Beam Computed Tomography to measure tooth diameter could be considered valid.
The research project was reviewed and approved by the Ethic Commission of Institute for Studies in Public Health of the Federal University of Rio de Janeiro.
In order to determine precision, reliability, and capacity of measurement repetition, ten pairs of plaster cast models, ten 45-degree radiographs, and ten tomographs were randomly selected and then measured twice by the same investigator, with a 10-day interval between both measurements. The intra-class correlation rate was as high as 0.98 for plaster cast models, 0.97 for radiographs, and 0.99 for tomographs, thus indicating reliability of the measurements performed by the investigator.
The descriptive statistics containing mean, standard deviation, minimum and maximum values for the sum of right and left permanent canines and premolars in Cone-Beam Computed Tomography (CBCT), in 45-degree radiographs, in 45-degree radiographs with correction of magnification and derived from Moyers' table and Tanaka-Johnston's formula are represented in Table 1.
The agreement between measurements of non-erupted teeth regarding tomography and those predicted by Moyers' table and Tanaka-Johnston's formula, including the 45-degree oblique radiographs, was evaluated by using both intra-class correlation rate and paired Student's t test at 95% confidence interval (p<0.05). The results revealed high agreement between tomographic and radiographic methods as well as low agreement between tomographs and other methods studied (Table 2).
Imaging diagnosis and study models are very important resources available in orthodontics. Within the context of conventional radiographic techniques, a varied number of exams (periapical, panoramic, teleradiographic, profile, posterior-anterior, occlusal, and 45-degree oblique) are routinely employed for orthodontic evaluation of the craniofacial region. Nevertheless, the conventional radiography is a two-dimensional representation of three-dimensional structures and therefore there are some drawbacks in terms of precision and spatial orientation, size, shape, and relationship between anatomical structures regarding this method.18 Differently from the radiography, which projects the X-ray exposed objects into one plane, the Cone-Beam Computed Tomography shows the relationships between structures in depth.14
Plaster cast models have limitations as well, since they have been traditionally measured manually by means of a calliper. Alternatively, measurements can be made on photocopies, photographs, holograms, and virtual models.19 Among some advantages regarding the digital methods in relation to the manual measurement, one can cite shorter procedure time, no need to store study models, and easy access to diagnostic records from anywhere.6
The use of Cone-Beam Computed Tomography to evaluate tooth diameter has not been tested. Despite this, other studies20-24 pointed out such a possibility as quantitative analyses using computed tomography were found to have high accuracy and precision. Measurements made directly on skull and on the tomographic image of the same skull were entirely similar. Precision and reproducibility of the method were confirmed by the presence of very few errors in the measurement repetitions, regardless of intra- and inter-examiner variability.14
In the evaluation of values regarding the sum of diameters of intra-osseous teeth, permanent pre-molars, and permanent canines measured on tomographic images and those measured using Moyers' table and Tanaka-Johnston's formula, statistical analysis showed low agreement between both methods. However, studies on medical tomographs of craniofacial region indicated that measurements up to 5% are clinically acceptable,22 and this figure is higher than that observed in the present study.
In the orthodontic treatment planning, individual variation represents an important factor.2 All methods for predicting mesial-distal diameter of canine and pre-molars, such as the Moyers' and Tanaka-Johnston's analyses, do not take into account the individuality and then under or over-estimate actual dental dimensions.16 With the use of Cone-Beam Computed Tomography, teeth are measured instead of being estimated. Tomographic exam of one of the patients revealed the presence of macrodontia and abnormal shape of the second pre-molars. By consulting the Moyers' table or Tanaka-Johnston's formula only, such information would not be taken into account and the space needed for the patient would be mistakenly predicted as being smaller. In another case, agenesis of second pre-molars was also observed on tomographs during the mixed-dentition analysis. For this patient, with absence of the second premolar, the Moyers' table and Tanaka-Johnston's formula could not be applied for purposes of comparison with the tomographic measurements, because it yields the sum of the canines and first and second premolars. For another, whose sum of measurements of lower incisors was so low that the Moyers' table could not be used, the comparison with the tomographic measurements was also not possible. The sample, therefore, consisted of 29 and 28 patients for the evaluation of tomography measurements with those suggested by the Tanaka-Johnston's formula and Moyers' table, respectively.
In turn, both radiographic and tomographic methods took into account individual variation (each tooth is measured during both exams), and a high agreement between them was observed. With regard to radiography, most cases (29.21%) involved rotated teeth. In this way, Cone-Beam Computed Tomography has some advantages in relation to the 45-degree oblique radiograph. The authors of the present study agree that three-dimensional imaging offers greater potential for quantitative evaluation of the skull and face because points are easily identified and structures are not overlapped. There is also the possibility of moving the image three-dimensionally, which allows visualization of the object at different angles.
Lima and Monnerat25 in 1992, have proposed correction of the 45-degree oblique teleradiography in order to determine the size of intra-osseous permanent canines and pre-molars. They suggested that measurements of teeth on radiographs should be multiplied by 0.928, thus resulting in high fidelity compared to real measurements.
Interestingly, the radiographic method having image magnification correction did not yield better results than the tomography (Table 2). The teeth measured on tomographs were often greater than those measured on oblique radiographs, and the radiographic magnification correction indeed enhanced such a difference.
According to Bernabé and Flores-Mir5; in 2005, the mixed-dentition analysis should present a minimum and known systematic error, allow easy replication by any basically trained operator, be quickly conducted, not require very sophisticated equipment, be directly applied to the mouth, and available for both dental arches. It is also important to emphasize that errors and time regarding the evaluation of the new method tend to be greater during this process of method change. As the examiner proceeds with the procedures and has the opportunity to evaluate more tomographs, less variations between the methods are observed, a finding also reported by Rheude et al17 in 2005.
The radiation dose of this imaging modality is equivalent to approximately one sixth of that necessary for a medical tomography. In addition, Cone-Beam Computed Tomography is very similar to dental radiographs, providing more reliable and extensive information14,19,20,21,26-30. Its modest application is due mainly to the high cost of softwares that allow viewing and editing images, since their acquisition, given the cost of dental radiographs, is financially attractive because the cost of the tomographic scan is equivalent to that of conventional orthodontic documentation14. Through the years, the likelihood is that such softwares become more accessible. The availability of such technology will undoubtedly extend the use and application of 3D images in orthodontics for clinical purposes23.
It is difficult to work with probabilities requiring accuracy, since human anatomy has inherent variations. There are several methods aimed to estimate the mesial-distal diameter of canines and pre-molars by means of tables, equations, and radiographs. Obtaining such values as closer to reality as possible by using these measurements is a challenge, since all may fail. The evaluation of the effectiveness of such methods is not meant to approve or reprove them, but to serve as a mechanism to assess how they can produce a reliable diagnosis. Therefore, allied to the prediction methods, a good professional sense should exist in order to elaborate diagnosis more effectively7.
Mixed-dentition analysis by the tomographic method is accurate and has some advantages in relation to other evaluated methods. It considers individual variations of dental anatomy, easy identification of points, no superposition of structures, and three-dimensional movement of image, which allows visualization at different angles.
To Research Support Foundation of Rio de Janeiro (FAPERJ) for financial assistance to obtain the Dolphin software, essential to implementing this project.
1. Shigenobu N, Hisano M, Shima S, Matsubara N, Soma K. Patterns of dental crowding in the lower arch and contributing factors. A statistical study. Angle Orthod. 2007 Mar;77(2):303-10. [ Links ]
2. Sayin MO, Türkkahraman H. Factors contributing to mandibular anterior crowding in the early mixed dentition. Angle Orthod. 2004 Dec;74(6):754-8. [ Links ]
3. Lima Martinelli F, Martinelli de Lima E, Rocha R, Souza Tirre-Araujo M. Prediction of lower permanent canine and premolars width by correlation methods. Angle Orthod. 2005 Sep;75(5):805-8. [ Links ]
4. Moyers RE. Handbook of orthodontics. 4th ed. Chicago: Year Book; 1988. [ Links ]
5. Bernabé E, Flores-Mir C. Are the lower incisors the best predictors for the unerupted canine and premolars sums? an analysis of a Peruvian sample. Angle Orthod. 2005 Mar;75(2):202-7. [ Links ]
6. Paredes V, Gandia JL, Cibrian R. New, fast, and accurate procedure to calibrate a 2-dimensional digital measurement method. Am J Orthod Dentofacial Orthop. 2005 Apr;127(4):518-9. [ Links ]
7. Marchionni VMT, Silva MCA, Araujo TM, Reis SRA. Avaliação da efetividade do método de Tanaka-Johnston para predição do diâmetro mésio-distal de caninos e pré-molares não-irrompidos. Pesqui Odontol Bras. 2001;15(1):35-40. [ Links ]
8. Cartwright LJ, Harvold E. Improved radiographic results in cephalometry through the use of high kilovoltage. J Can Dent Assoc. 1954;1(6):251-4. [ Links ]
9. Barber TK, Pruzansky S, Lauterstein A, Kindelperger R. Application of roentgenographic cephalometry to pedodontic research. J Dent Child. 1960;7(2nd quart.):97-106. [ Links ]
10. Barber TK, Pruzansky S, Kindelperger R. An evaluation of the oblique cephalometric film. J Dent Child. 1961;28:94-105. [ Links ]
11. Ingervall B, Lennartsson B. Prediction of breadth of permanent canines and premolars in the mixed dentition. Angle Orthod. 1978 Jan;48(1):62-9. [ Links ]
12. Paula S, Almeida MA, Lee PC. Prediction of mesiodistal diameter of unerupted lower canines and premolars using 45 degrees cephalometric radiography. Am J Orthod Dentofacial Orthop. 1995 Mar;107(3):309-14. [ Links ]
13. Bronzi ES, Sakima T, Sakima MT. Telerradiografia em norma de 45 graus: uma revisão de literatura. Rev Fac Odontol Inst Amaz Ens Sup. 2004 jul-dez;1:24-35. [ Links ]
14. Garib DG, Raymundo R Jr, Raymundo MV, Raymundo DV, Ferreira SN. Tomografia computadorizada de feixe cônico (Cone beam): entendendo este novo método de diagnóstico por imagem com aplicabilidade na Ortodontia. Rev Dental Press Ortod Ortop Facial. 2007 mar-abr;12(2):139-56. [ Links ]
15. Motta AT. Avaliação da cirurgia de avanço mandibular por meio da superposição de modelos tridimensionais. [tese]. Rio de Janeiro (RJ): Universidade Estadual do Rio de Janeiro; 2007. [ Links ]
16. Melgaço CA, Sousa Araújo MT, Oliveira Ruellas AC. Mandibular permanent first molar and incisor width as predictor of mandibular canine and premolar width. Am J Orthod Dentofacial Orthop. 2007 Sep;132(3):340-5. [ Links ]
17. Rheude B, Sadowsky PL, Ferriera A, Jacobson A. An evaluation of the use of digital study models in orthodontic diagnosis and treatment planning. Angle Orthod. 2005 May;75(3):300-4. [ Links ]
18. Oliveira AT. Aplicações da tomografia computadorizada cone beam em ortodontia: revisão de literatura [monografia]. Rio de Janeiro (RJ): Marinha do Brasil; 2007. [ Links ]
19. Zilberman O, Huggare JA, Parikakis KA. Evaluation of the validity of tooth size and arch width measurements using conventional and three-dimensional virtual orthodontic models. Angle Orthod. 2003 Jun;73(3):301-6. [ Links ]
20. Mozzo P, Procacci C, Tacconi A, Martini PT, Andreis IA. A new volumetric CT machine for dental imaging based on the cone-beam technique: preliminary results. Eur Radiol. 1998;8(9):1558-64. [ Links ]
21. Lascala CA, Panella J, Marques MM. Analysis of the accuracy of linear measurements obtained by cone beam computed tomography (CBCT-NewTom). Dentomaxillofac Radiol. 2004 Sep;33(5):291-4. [ Links ]
22. Hilgers ML, Scarfe WC, Scheetz JP, Farman AG. Accuracy of linear temporomandibular joint measurements with cone beam computed tomography and digital cephalometric radiography. Am J Orthod Dentofacial Orthop. 2005 Dec;128(6):803-11. [ Links ]
23. Periago DR, Scarfe WC, Moshiri M, Scheetz JP, Silveira AM, Farman AG. Linear accuracy and reliability of cone beam CT derived 3-dimensional images constructed using an orthodontic volumetric rendering program. Angle Orthod. 2008 May;78(3):387-95. [ Links ]
24. Brown AA, Scarfe WC, Scheetz JP, Silveira AM, Farman AG. Linear accuracy of cone beam CT derived 3D images. Angle Orthod. 2009 Jan;79(1):150-7. [ Links ]
25. Lima EMS, Monnerat ME. Comparação das predições do somatório dos diâmetros mésio-distais de pré-molares e caninos permanentes inferiores com seus valores reais [dissertação]. Rio de Janeiro (RJ): Universidade Federal do Rio de Janeiro; 1992. [ Links ]
26. Scarfe WC, Farman AG, Sukovic P. Clinical applications of cone-beam computed tomography in dental practice. J Can Dent Assoc. 2006 Feb;72(1):75-80. [ Links ]
27. Holberg C, Steinhäuser S, Geis P, Rudzki-Janson I. Cone-beam computed tomography in orthodontics: benefits and limitations. J Orofac Orthop. 2005 Nov;66(6):434-44. [ Links ]
28. Kau CH, Richmond S, Palomo JM, Hans MG. Three-dimensional cone beam computerized tomography in orthodontics. J Orthod. 2005 Dec;32(4):282-93. [ Links ]
29. Nakajima A, Sameshima GT, Arai Y, Homme Y, Shimizu N, Dougherty H Sr. Two- and three-dimensional orthodontic imaging using limited cone beam-computed tomography. Angle Orthod. 2005 Nov;75(6):895-903. [ Links ]
30. Ludlow JB, Davies-Ludlow LE, Brooks SL, Howerton WB. Dosimetry of 3 CBCT devices for oral and maxillofacial radiology: CB Mercuray, NewTom 3G and i-CAT. Dentomaxillofac Radiol. 2006 Jul;35(4):219-26. [ Links ]
Contact address: Submitted: June
Antônio Carlos de Oliveira Ruellas
Av. Professor Rodolpho Paulo Rocco - Cidade Universitária
CEP: 21.941-590 - Rio de Janeiro/RJ, Brazil
Revised and accepted: August 2010