- Citado por SciELO
Revista de Microbiologia
versão impressa ISSN 0001-3714
GAETTI-JARDIM JUNIOR, Elerson e AVILA-CAMPOS, Mario Julio. Bacteriocin-like activity of oral Fusobacterium nucleatum isolated from human and non-human primates. Rev. Microbiol. [online]. 1999, vol.30, n.4, pp.324-346. ISSN 0001-3714. http://dx.doi.org/10.1590/S0001-37141999000400009.
Fusobacterium nucleatum is indigenous of the human oral cavity and has been involved in different infectious processes. The production of bacteriocin-like substances may be important in regulation of bacterial microbiota in oral cavity. The ability to produce bacteriocin-like substances by 80 oral F. nucleatum isolates obtained from periodontal patients, healthy individuals and Cebus apella monkeys, was examinated. 17.5% of all tested isolates showed auto-antagonism and 78.8% iso- or hetero-antagonism. No isolate from monkey was capable to produce auto-inhibition. In this study, the antagonistic substances production was variable in all tested isolates. Most of the F. nucleatum showed antagonistic activity against tested reference strains. These data suggest a possible participation of these substances on the oral microbial ecology in humans and animals. However, the role of bacteriocins in regulating dental plaque microbiota in vivo is discussed.
Palavras-chave : Fusobacterium nucleatum; bacteriocin-like substance; oral bacteria.