Revista de Microbiologia
versão impressa ISSN 0001-3714
SIMONI, Isabela Cristina et al. Susceptibility of cell lines to avian viruses. Rev. Microbiol. [online]. 1999, vol.30, n.4, pp. 373-376. ISSN 0001-3714. http://dx.doi.org/10.1590/S0001-37141999000400015.
The susceptibility of the five cell lines - IB-RS-2, RK-13, Vero, BHK-21, CER - to reovirus S1133 and infectious bursal disease virus (IBDV vaccine GBV-8 strain) was studied to better define satisfactory and sensitive cell culture systems. Cultures were compared for presence of CPE, virus titers and detection of viral RNA. CPE and viral RNA were detected in CER and BHK-21 cells after reovirus inoculation and in RK-13 cell line after IBDV inoculation and with high virus titers. Virus replication by production of low virus titers occurred in IB-RS-2 and Vero cells with reovirus and in BHK-21 cell line with IBDV.
Palavras-chave : reovirus; infectious bursal disease virus; cell lines; susceptibility.