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Anais da Academia Brasileira de Ciências

Print version ISSN 0001-3765

Abstract

PINHEIRO, Eduardo A.A. et al. Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity. An. Acad. Bras. Ciênc. [online]. 2013, vol.85, n.4, pp.1247-1253.  Epub Oct 21, 2013. ISSN 0001-3765.  http://dx.doi.org/10.1590/0001-3765201395512.

The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.

Keywords : chemical constituents; antimicrobial assay; Aspergillus; Bauhinia guianensis.

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