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Anais da Academia Brasileira de Ciências

Print version ISSN 0001-3765On-line version ISSN 1678-2690

Abstract

MESQUITA, MARIANA Q. et al. An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy. An. Acad. Bras. Ciênc. [online]. 2018, vol.90, n.1, suppl.2, pp.1101-1130. ISSN 0001-3765.  https://doi.org/10.1590/0001-3765201720170800.

Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.

Keywords : Photodynamic therapy; Drug delivery; Liposomes; Silica nanoparticles; Gold nanoparticles; Polymeric micelles.

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