Arquivos Brasileiros de Endocrinologia & Metabologia
versão impressa ISSN 0004-2730
LIMA, Josivan G. et al. Postprandial dyslipidemia as a precocious finding in subjects with low cardiovascular risk. Arq Bras Endocrinol Metab [online]. 2002, vol.46, n.3, pp. 249-254. ISSN 0004-2730. http://dx.doi.org/10.1590/S0004-27302002000300006.
OBJECTIVE: to show a correlation between postprandial hypertriglyceridemia and cardiovascular risk factors to atherogenesis. RESEARCH DESIGN AND METHODS: 47 (30 women and 17 men, 40.5 ± 14.9years, body mass index: 26.1 ± 5.4kg/m2) non diabetic volunteers with normal (<200mg/dl) triglycerides were studied. Triglycerides, HDL-cholesterol and total cholesterol were measured before (basal), 3 and 5 hours after a 70g-lipid standardized test meal. RESULTS: patients with 3 hours postprandial hypertriglycerides higher than the 2nd Quartile (164.8mg/dl), in spite of normal fasting triglycerides, have higher BMI (28.1 ± 5.6 vs. 24.2 ± 4.5kg/m2; p= 0.008), abdominal circumference (95.7 vs. 84.1cm; p= 0.001), waist/hip ratio (0.92 vs. 0.86; p= 0.008) and diastolic pressure (83.1 vs. 77.2mmHg; p= 0.02) and lower HDL (39.1 vs. 48.3mg/dl; p= 0.008). CONCLUSIONS: Postprandial hypertriglyceridemia related well with others risk factors, even in patients with normal fasting triglycerides.
Palavras-chave : Postprandial lipemia; Atherogenesis; X syndrome; Remanescents.