SciELO - Scientific Electronic Library Online

 
vol.48 issue3Myocardial perfusion scintigraphy in type 2 diabetic patients with atypical chest painStudy of the oral manifestations in diabetic children and their correlation variables author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Arquivos Brasileiros de Endocrinologia & Metabologia

On-line version ISSN 1677-9487

Abstract

SILVA, Gisleine E.C. da et al. Absence of hypolipidemic effect of Solanum melongena L. (eggplant) on hyperlipidemic patients. Arq Bras Endocrinol Metab [online]. 2004, vol.48, n.3, pp.368-373. ISSN 1677-9487.  http://dx.doi.org/10.1590/S0004-27302004000300006.

In this study we investigated the hypolipidemic potential of dried powdered fruits of eggplant (Solanum melongena), which has been commercialized in Brazil to treat human hyperlipidemia. Thus, a double-blind placebo-controlled study of the effectiveness of oral Solanum melongena (SM) was conducted. The study consisted of 41 hyperlipidemic volunteers allocated to active treatment (n= 21) or placebo (n= 20). Each volunteer received two capsules containing SM (450mg) or placebo (450mg) twice daily and were followed monthly. The dose of SM used corresponds to that given to treat hyperlipidemia in Brazil. After 3 months, serum total cholesterol, LDL-c and LDL-c/HDL-c decreased (p<0.05) in the group treated with SM. However similar effect was also observed in the placebo group. The other parameters, including serum triglycerides, HDL-c, VLDL-c, AST, ALT, gGT, glucose and body mass index, showed no significant changes. We conclude that SM, at least in the form commercialized in the Brazil (dried powdered fruits), require further clinical trials before being recommended to treat hyperlipidemia.

Keywords : Solanum melongena; Eggplant; Hyperlipidemia; Herbal medicine.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License