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Arquivos Brasileiros de Endocrinologia & Metabologia
On-line version ISSN 1677-9487
CERUTTI, Janete M.. Nodule diagnosed as follicular patterned lesion: are biomarkers the promise?. Arq Bras Endocrinol Metab [online]. 2007, vol.51, n.5, pp.832-842. ISSN 1677-9487. http://dx.doi.org/10.1590/S0004-27302007000500022.
There are an increasing number of thyroid nodules found by ultrasound and sampled by fine needle aspiration (FNA). A clinical problem is the accurate distinction between benign and malignant forms of follicular lesion. In this review we discuss the thyroid lesions that are common sources of diagnostic error, and grouped together as follicular patterned lesion, and the molecular markers identified by us and others, and that are able to distinguish the benign from the malignant ones.
Keywords : Follicular patterned; Biomarkers; Follicular thyroid adenoma; Follicular thyroid carcinoma; FNA; Diagnosis.