SciELO - Scientific Electronic Library Online

 
vol.53 issue9The inclusion of new techniques of chromosome analysis has improved the cytogenetic profile of Turner syndromeBody mass index increase after the age of 20 and associations with risk or protection factors for chronic non-communicable diseases author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Arquivos Brasileiros de Endocrinologia & Metabologia

On-line version ISSN 1677-9487

Abstract

ROSARIO, Pedro Weslley; SALLES, Daniela Santos; BESSA, Breno  and  PURISCH, Saulo. Low false-negative rate of cytology in thyroid nodules > 4 cm. Arq Bras Endocrinol Metab [online]. 2009, vol.53, n.9, pp.1143-1145. ISSN 1677-9487.  http://dx.doi.org/10.1590/S0004-27302009000900011.

OBJECTIVE: To report the results of cytology and histology obtained for a series of systematically resected thyroid nodules > 4 cm. METHODS: A group of 151 patients with thyroid nodules > 4 cm was submitted to surgery despite the cytology result. RESULTS: Malignancy was confirmed histologically in 22.5% of the patients. Excluding cases of insufficient material, cytology was benign in only 3/31 carcinomas (90.3% sensitivity). The frequency of malignancy was 35% among nodules with indeterminate cytology (follicular neoplasm), and there was a predominance (77%) of papillary carcinoma. The negative predictive value of benign cytology was 96.4%. CONCLUSIONS: The false-negative rate of cytology in thyroid nodules > 4 cm does not justify systematic resection of these nodules in asymptomatic patients with benign cytology.

Keywords : Thyroid nodule; cytology; benign.

        · abstract in Portuguese     · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License