Abstract

VIGARIO, Patrícia dos Santos et al. Impaired functional and hemodynamic response to graded exercise testing and its recovery in patients with subclinical hyperthyroidism. Arq Bras Endocrinol Metab [online]. 2011, vol.55, n.3, pp. 203-212. ISSN 0004-2730.  http://dx.doi.org/10.1590/S0004-27302011000300005.

OBJECTIVE: To evaluate the functional and hemodynamic responses during exercise and its recovery in patients with subclinical hyperthyroidism (SCH). SUBJECTS AND METHODS: A cross-sectional study was carried out with 29 patients on TSH-suppressive therapy with levothyroxine for thyroid carcinoma and 35 euthyroid subjects. All volunteers underwent a cardiopulmonary exercise testing on a treadmill and functional and hemodynamic variables were measured during exercise and its recovery. RESULTS: SCH patients showed impaired functional response to exercise, marked by lower values for oxygen consumption and exercise duration in addition to premature achievement of the anaerobic threshold. Heart-rate and blood pressure recovery immediately after exercise were slower among SCH patients when compared to euthyroid subjects. CONCLUSION: SCH is associated with impaired functional and hemodynamic responses during exercise and its recovery.

Keywords : Hyperthyroidism; oxygen consumption; heart-rate; blood pressure.