Abstract

BARBOSA JUNIOR, José Bonifácio et al. Adenovirus conjunctivitis diagnosis using RPS Adenodetector^®. Arq. Bras. Oftalmol. [online]. 2007, vol.70, n.3, pp. 441-444. ISSN 0004-2749.  http://dx.doi.org/10.1590/S0004-27492007000300010.

PURPOSE: To evaluate the RPS Adenodetector^®, a rapid immunochromatographic test, in the diagnosis of patients with clinical overt adenoviral conjunctivitis. METHODS: Consecutive case series. Patients underwent conjunctiva scraping for RPS Adenodetector^® test and culture to identify adenovirus. RESULTS: A total of 11 patients were studied, and 10 had unilateral disease. Five (45.5%) had symptoms for 2 days, 5 for three days, and 1 for 7 days. Adenovirus culture was positive in 8 patients (73%) and RPS Adenodetector^® was positive in 9 (82%) patients. Eight patients had adenovirus identification by both methods. In one patient the RPS Adenodetector^® was positive in contrast to a negative culture. The two patients revealing negative RPS Adenodetector^® results also had negative cultures. The sensitivity was 100% and the specificity was 67%. CONCLUSION: The RPS Adenodetector^® is a useful tool in the rapid diagnosis of adenovirus conjunctivitis and may contribute to the spread control of this highly contagious disease.

Keywords : Conjunctivitis, viral [diagnosis]; Adenoviridae infections; Chromatography; Virus cultivation [methods].