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Arquivos Brasileiros de Oftalmologia
On-line version ISSN 1678-2925
ARANTES, Tiago Eugênio Faria e; NASCIMENTO, Vinícius Paganini; MAIA JUNIOR, Otacílio de Oliveira and TAKAHASHI, Walter Yukihiko. Bevacizumab (Avastin®) in treatment of choroidal neovascularization secondary to age-related macular degeneration: a case report. Arq. Bras. Oftalmol. [online]. 2007, vol.70, n.6, pp. 1016-1020. ISSN 1678-2925. http://dx.doi.org/10.1590/S0004-27492007000600025.
The antiangiogenic drugs have been recently introduced in the therapeutic armamentarium of choroidal neovascularization. The purpose of this report is to describe a case of occult choroidal neovascularization with extensive retinal pigment epithelial detachment treated with intravitreal bevacizumab (Avastin®). The efficacy of the medication was evaluated by means of visual acuity and complementary exams (fluorescein angiography, indocyanine green video angiography and optical coherence tomography). After three intravitreal injections of bevacizumab a satisfactory anatomic and visual response was achieved, showing benefits of the drug, despite the extensive retinal pigment epithelial detachment associated with occult choroidal neovascularization.
Keywords : Macular degeneration [complications]; Macula lutea; Choroidal neovascularization [etiology]; Choroidal neovascularization [drug therapy]; Angiogenesis inhibitors [therapeutic use]; Vascular endothelial growth factors; Fluorescein angiography; Tomography, optical coherence; Female; Humans; Aged; Case reports.