Arquivos Brasileiros de Oftalmologia
Print version ISSN 0004-2749
GOMES, José Álvaro Pereira et al. Transplantation of allogenic limbal epithelial stem cells cultivated ex vivo on amniotic membrane: case report. Arq. Bras. Oftalmol. [online]. 2009, vol.72, n.2, pp. 254-256. ISSN 0004-2749. http://dx.doi.org/10.1590/S0004-27492009000200025.
Case report of a patient who developed failure of an allogenic living related conjunctival limbal transplantation in the right eye after an episode of epidemic keratoconjunctivitis. After a few months, she underwent transplantation of allogenic limbal epithelial stem cells cultivated ex vivo on amniotic membrane (first case in Brazil). The patient evolved with total corneal epithelialization and improvement of the visual acuity. Three months after the surgery, peripheral superficial neovascularization with worsening of the corneal transparency was observed. The vision remained 0.1 after one year of the transplantation.
Keywords : Epithelium, corneal; Limbus corneae; Stem cells transplantation; Amnion; Case reports.