SciELO - Scientific Electronic Library Online

 
vol.36 issue4Treatment of ulcerative colitis in child with enemas containing butyrate: case reportCeliac disease serum antibodies author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Arquivos de Gastroenterologia

Print version ISSN 0004-2803On-line version ISSN 1678-4219

Abstract

SDEPANIAN, Vera Lucia; MORAIS, Mauro Batista de  and  FAGUNDES-NETO, Ulysses. Celiac disease: evolution in knowledge since its original centennial description up to the present days. Arq. Gastroenterol. [online]. 1999, vol.36, n.4, pp.244-257. ISSN 1678-4219.  https://doi.org/10.1590/S0004-28031999000400013.

In the recent past, some celiac disease features have been discussed in literature specially related to genetic susceptibility, pathogenesis, clinical presentation and diagnostic criteria. Immunological abnormalities characteristic of celiac disease, such as circulating antibodies and increased numbers of intra-epithelial lymphocytes containing a high percentage of gamma-delta T cells have been demonstrated. Other pictures of clinical presentation besides the classical one deserve attention namely short stature, iron-resistant anaemia, enamel hypoplasia, constipation, neurological manifestation and osteoporosis, among others. Asymptomatic presentation has been recognized since development of serological markers such as anti-gliadin, anti-reticulin and anti-endomysium antibodies. Up to now, small intestinal biopsy is the only decisive diagnostic approach. A Federal law has recently imposed food manufactures to place labels informing the presence of gluten in industrialized foods in Brazil. Lately there has been an increase in celiac disease patients registered in the Brazilian Celiac Association.

Keywords : Celiac disease; Gluten.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License