SciELO - Scientific Electronic Library Online

 
vol.38 issue3Assessment of gliadin in pharmaceutical products: important information to the orientation of celiac disease patientsElectromanometry study of the upper esophageal sphincter before and after esophageal infusion with HCl 0,1N: experimental study in dog author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Arquivos de Gastroenterologia

Print version ISSN 0004-2803On-line version ISSN 1678-4219

Abstract

FRANCHI-TEIXEIRA, Antonio Roberto; JORGE, Gracinda L.; LEONARDI, Luís Sérgio  and  SAAD, Mário José Abdalla. Renal glucose release in rabbits submitted to total functional hepatectomy and norepinephrine infusion. Arq. Gastroenterol. [online]. 2001, vol.38, n.3, pp.183-188. ISSN 1678-4219.  https://doi.org/10.1590/S0004-28032001000300008.

Aim — To study the possible endogenous sources of glucose in the absence of the liver (equivalent to the anhepatic period of liver transplantation). Material and Methods - A experimental model of total functional hepatectomy in anesthetised rabbits was developed. The aorta and the right renal vein were catheterised in order to collect blood samples to measure glucose contents. The animals were divided into two groups: group 1, 5 animals underwent only norepinephrine infusion; group 2, 15 animals underwent norepinephrine infusion and submitted to total functional hepatectomy. Results - In group 2, before the hepatectomy, arterial glucose levels were higher than venous ones and after the liver removal, the venous levels became higher than the arterial ones. This pattern showed an inversion in the glicemic curves. In group 1 this pattern was not observed. Conclusion - The glicemic curves behavior observed in group 2 is not due to norepinephrine infusion, but represents renal glucose release after total functional hepatectomy.

Keywords : Hepatectomy; Glucose [metabolism]; Norepinephrine; Rabbits.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License