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Arquivos de Gastroenterologia

Print version ISSN 0004-2803On-line version ISSN 1678-4219


DIAZ, Norys Josefina; PATRICIO, Francy Silva  and  FAGUNDES-NETO, Ulysses. Allergic colitis: clinical and morphological aspects in infants with rectal bleeding. Arq. Gastroenterol. [online]. 2002, vol.39, n.4, pp.260-267. ISSN 1678-4219.

BACKGROUND: Recent studies indicate the importance of eosinophilis infiltrated in the rectal mucous which jointly with the clinical features can serve to establish the diagnostic of allergic colitis. AIM: To describe prospectively, the clinical features and morphological abnormalities of the rectal mucosa in patients with rectal bleeding and clinical diagnosis of cow's milk allergy. METHODS: Clinical features of 20 infants under 6 months of age were described. Morphological findings in rectal mucosa were compared with control group, with suspicion of congenital megacolon. RESULTS: The mean age of the patients was 97 ± 47 days, rectal bleeding started before 120 days in 85% of them; 40% were breastfed, 60% cow's milk formula or both. The most striking morphological feature, in 18 patients, was eosinophilic infiltration in the rectal mucosa. There was a significant statistical difference when these values were compared with control group. CONCLUSIONS: The increased number of eosinophils in the rectal mucosa represent the most important characteristic of allergic colitis, in patients under 6 months, with rectal bleeding, when breastfed, cow's milk formula or both.

Keywords : Milk hypersensitivity; Colitis; Intestinal mucosa; Infant.

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