Arquivos de Gastroenterologia
Print version ISSN 0004-2803
RESENDE, Vivian; PETROIANU, Andy; ALVES, Marlene Soares Dias and ALBERTI, Luiz Ronaldo. Effect of jaundice on fertility, ovarian morphology and fetal development in rats. Arq. Gastroenterol. [online]. 2008, vol.45, n.3, pp. 249-251. ISSN 0004-2803. http://dx.doi.org/10.1590/S0004-28032008000300016.
The effect of jaundice on the reproductive capacity, ovarian morphology and fetal development in rats was assessed in 53 sexually mature rats divided into two groups: group 1 (n = 28) - submitted to ligature of the biliopancreatic duct and group 2 (n = 25) - control - submitted only to sham operation. In jaundice rats fertilization is viable, the reproductive capacity is intensive reduced, the estrus cycles becomes irregular, the corpi lutea is presented in regression, the gravidic lutea is not modified increasing gradually during the pregnancy and the fetal development is seriously impaired.
Keywords : Hyperbilirubinemia; Jaundice, obstructive; Fertilization; Fetal development; Estrous cycle; Rats.