SciELO - Scientific Electronic Library Online

vol.45 número1Herpetic brainstem encephalitis: report of a post-mortem case studied electron microscopically and immunohisiochemicallyGM1 - type 1 glanglio sido sis: anatomo-clinic study of a case índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados


Arquivos de Neuro-Psiquiatria

versión impresa ISSN 0004-282X


KOUYOUMDJIAN, João Aris et al. Creutzfeldt-Jakob disease: a case report. Arq. Neuro-Psiquiatr. [online]. 1987, vol.45, n.1, pp.53-59. ISSN 0004-282X.

A case of Creutzfeldt-Jakob disease (CJD) in a 76 year-old man is presented. The clinical picture included a rapid progressive dementia associated with ataxia, global afasia, myoclonus and pyramidal signs; death occurred after about 4 months. There was an antecedent of chemical trauma caused by plant liquid on right eye 12 to 18 months before. The electroencephalogram showed diffuse slow activity and the neuropathological findings were typical. The detection of a protein called "prion" or PrP27-30 in the scrapie and the finding that some proteins isolated from brain of patients with CJD have reacted with antibodies raised against it have improved the knowledge about the infectious agent. The recent reports of young patients with CJD after human growth hormone therapy prepared from pools of pituitary glands obtained at autopsy are alarming and probably new cases will be described.

        · resumen en Portugués     · texto en Portugués     · Portugués ( pdf epdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons