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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X


CIANCIARULLO, Thais S.; NEVES, Beatrice Maria J.  and  STAVALE, João N.. Primitive neuroectodermal tumor of the central nervous system: report of four cases. Arq. Neuro-Psiquiatr. [online]. 1994, vol.52, n.3, pp.392-395. ISSN 0004-282X.

The clinicopathological and immunohistochemical features of four cases of primitive neuroectodermal tumors of the central nervous system were investigated. Three patients died. All cases showed vimentin-positive cells with the morphology of neoplastic cells and one case showed glial fibrillary acidic protein, neuron-specific enolase and neurofilament protein-positive cell. The present study indicates that this group of tumors have bad prognostics and may show immunocytochemical features indicating glial and/or neuronal differentiation.

Keywords : primitive neuroectodermal tumor; immunohistochemistry; differentiation.

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