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Local IgG synthesis in three pediatric patients with cuban epidemic neuropathy

Sintesis local de IgG en tres pacientes pediátricos com neuropatía epidêmica cubana

Three pediatric patients with Cuban epidemic neuropathy were studied. Cerebrospinal fluid and sera were simultaneously obtained. Albumin and IgG were quantified by immunodifusion. Albumin quotient and local synthesis of IgG were calculated by Reiber/Felgenhauer formula. A patient with optic neuritis had a dysfunction of the blood-cerebrospinal fluid barrier. All the group had local synthesis of IgG.

Cuban epidemic neuropathy; optic neuritis; peripheral neuropathy; cerebrospinal fluid; intrathecal synthesis


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