SciELO - Scientific Electronic Library Online

vol.55 issue3BNeuroimage findings in hepatocerebral degeneration induced by hemochromatosisBinswanger's disease: case report author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X


PY, Marco O.  and  ANDRE, Charles. Acute disseminated encephalomyelitis: association with meningococcal A and C vaccine: case report. Arq. Neuro-Psiquiatr. [online]. 1997, vol.55, n.3B, pp.632-635. ISSN 0004-282X.

A 25-year-old woman developed acute disseminated post-vaccinal encephalomyelitis (ADEM) following vaccination with A plus C meningococcal vaccine (Pasteur-Merieux). Fast disappearance of symptoms and gradual resolution of MR1 demyelinating lesions occurred after steroid treatment with high doses of intravenous methylprednisolone. To our knowledge, ADEM has not been previously described in association with meningococcal vaccine. Although most cases of ADEM occur following viral infections and vaccination, the syndrome has previously been related to leptospirosis and Mycoplasma pneumoniae infections. This suggests that it may also be related to exposure to polysaccharide-protein vaccines such as the Group A plus Group C meningococcal vaccine.

Keywords : encephalomyelitis acute disseminated; bacterial vaccine adverse effects; Neisseria meningitidis.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License