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Arquivos de Neuro-Psiquiatria
Print version ISSN 0004-282X
BLEGGI-TORRES, LUIZ F. et al. Choroid plexus carcinoma: report of fifteen cases. Arq. Neuro-Psiquiatr. [online]. 2000, vol.58, n.2B, pp. 505-511. ISSN 0004-282X. http://dx.doi.org/10.1590/S0004-282X2000000300017.
Choroid plexus carcinoma (CPC) are rare central nervous system tumours derived from choroid plexus epithelium, affecting mainly children under 3 years of age. We present a clinical, epidemiological and histopathological study of 15 cases of CPC. Ten patients were male. Age ranged from 4 months to 21 years (mean=3,4). The lateral ventricles were affected in 73,3% of cases. Main symptom were: hydrocephalus (62.5%), intracranial hypertension (25%) and convulsion (12.5%). The patients were treated by surgery with partial resection in 75% of cases and total resection in 25%. There was one death due to surgical complication, 85.7% of patients had recurrence of tumours with mean survival rate of 13.6% months after diagnosis. Only one patient remain alive 5 years after initial treatment. These results support the poor prognosis and high mortality rate of CPC.
Keywords : brain neoplasm; choroid plexus tumours; choroid plexus carcinoma; immunohistochemistry.