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Sotos syndrome (cerebral gigantism): analysis of 8 cases

Síndrome de Sotos (gigantismo cerebral): análise de 8 casos

Sotos syndrome or cerebral gigantism is characterized by macrocephaly, overgrowth, mental retardation and central nervous system abnormalities. Congenital heart defects may be present. We report 8 patients with this syndrome and relate their clinical features, neuroimaging and echocardiographic findings.

Sotos syndrome; cerebral gigantism; macrocephaly; mental retardation


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