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Arquivos de Neuro-Psiquiatria
On-line version ISSN 1678-4227
PASQUALOTTO, Alessandro Comarú; MATTOS, Alice J.Z. de and ROCHA, Marineide Melo. Progressive multifocal leukoencephalopathy confirmed by PCR: case report. Arq. Neuro-Psiquiatr. [online]. 2004, vol.62, n.2b, pp. 550-554. ISSN 1678-4227. http://dx.doi.org/10.1590/S0004-282X2004000300034.
A case of progressive multifocal leukoencephalopathy (PML) is presented, with literature review. PML diagnosis and its differential diagnosis are presented, with emphasis on neuroradiology, cerebrospinal fluid analysis and polymerase chain reaction studies. The prognosis of PML is usually poor, with a median survival of 1-6 months. There is yet no proven effective treatment for this condition; HAART has become the standard of care for these patients.
Keywords : progressive multifocal leukoencephalopathy; HAART; HIV infections; AIDS; JC virus; polymerase chain reaction.