Arquivos de Neuro-Psiquiatria
Print version ISSN 0004-282X
MARIA VILLA, Andrés et al. Interferon b-1a in chronic inflammatory demyelinating polyneuropathy: case report. Arq. Neuro-Psiquiatr. [online]. 2004, vol.62, n.3b, pp. 892-894. ISSN 0004-282X. http://dx.doi.org/10.1590/S0004-282X2004000500031.
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated neuropathy. It presents with a course of progression which may be slow and steady or step-wise or relapsing. Sensory ataxic polyneuropathy may be the only clinical manifestation of this disease. Treatment with interferon b1a (INF b1a) has been tried with different results in patients who were refractory to other, more conventional, immunomodulatory therapies. Here we report on a patient who had a relapsing form of pure sensory ataxic CIDP and who failed to respond to intravenous human immunoglobulin. He was put on INF b1a for 3 years. During this period he suffered no relapses while his condition stabilized.
Keywords : CIDP; peripheral neuropathy; interferon b (IFN b).