Resumo

LAKS, Jerson et al. Functional and motor response to low dose olanzapine in huntington's disease: case report. Arq. Neuro-Psiquiatr. [online]. 2004, vol.62, n.4, pp.1092-1094. ISSN 1678-4227.  https://doi.org/10.1590/S0004-282X2004000600030.

Previous reports on the use of olanzapine in Huntington's disease (HD) used doses ranging from 10-30 mg. We report a case of HD with marked delusions and behavioral impairment assessed by the Unified Huntington's Disease Rating Scale at baseline and four months later treated with a low dose of olanzapine. The patient improved in motor, psychiatric and activity of daily living symptoms after four months of treatment. The response to a low dose of olanzapine in HD may be an indicator of efficacy in similar cases. Further randomized controlled trials can properly assess these findings.

Palavras-chave : Huntington's disease; olanzapine; behavioral abnormalities; functional capacity.

        · resumo em Português     · texto em Inglês     · Inglês ( pdf )