Abstract

HERCULANO, Marco Antonio; TELLA JR, Oswaldo Ignácio de; PRANDINI, Mirto Nelso  and  ALVES, Maria Teresa de Seixas. Inhibition of peridural fibrosis after laminectomy using biological sheet in rat model. Arq. Neuro-Psiquiatr. [online]. 2006, vol.64, n.2a, pp.259-263. ISSN 0004-282X.  http://dx.doi.org/10.1590/S0004-282X2006000200016.

The prevention of fibrosis after lumbar and thoracic laminectomies by avoiding herniation of muscular tissue was studied using Wistar-EPM rats with a biological membrane made of decorticated bone of bovine material. The rats were sacrified after eight, sixteen and twenty four weeks and the materal was sent to anatomopathological study. This membrane proved to be biocompatible and its efficacy was seen by allowing formation of bone and preventing muscular tissue invasion of the epidural space and avoiding adherences.

Keywords : biological membrane; laminectomy; bovine cortical bone; fibrosis.

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