SciELO - Scientific Electronic Library Online

vol.65 issue1Probable causal link between epilepsy and sleep apnea: case reportDermoid cyst of the anterior fontanelle in adults: case report author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282XOn-line version ISSN 1678-4227


MATTA, André Palma da Cunha  and  GONSALVES, Márcia de Castro Diniz. Merosin-positive congenital muscular dystrophy: neuroimaging findings. Arq. Neuro-Psiquiatr. [online]. 2007, vol.65, n.1, pp.167-169. ISSN 0004-282X.

Congenital muscle dystrophy (CMD) is a heterogeneous group of autosomal recessive myopathies. It is known that CMD may affect the central nervous system (CNS). Some authors have shown that merosin-negative CMD patients may have encephalic metabolic disturbances. In order to study metabolic changes within the brain, the authors performed a magnetic resonance spectroscopy (MRS) study in a 1-year-old girl with merosin-positive CMD (MP-CMD). MRS of brain demonstrated that NAA/Cr ratio was decreased (1.52), while Cho/Cr ratio was increased (1.78). These findings suggest that metabolic changes in CNS can also be found in patients with MP-CMD.

Keywords : congenital muscle dystrophy; merosin; magnetic resonance.

        · abstract in Portuguese     · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License