SciELO - Scientific Electronic Library Online

 
vol.65 número3ACefaléias primárias: abordagem diagnóstica por médicos não-neurologistasO valor do potencial evocado auditivo em decisão clínica em paciente com síndrome hipóxico-isquêmica índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Arquivos de Neuro-Psiquiatria

versão impressa ISSN 0004-282Xversão On-line ISSN 1678-4227

Resumo

FABIANI, Giorgio et al. Liver transplantion in a patient with rapid onset parkinsonism-dementia complex induced by manganism secondary to liver failure. Arq. Neuro-Psiquiatr. [online]. 2007, vol.65, n.3a, pp.685-688. ISSN 0004-282X.  http://dx.doi.org/10.1590/S0004-282X2007000400027.

Bilateral and symmetric globus-pallidus hyperintensities are observed on T1-weighted MRI in most of the patients with chronic liver failure, due to manganese accumulation. We report a 53-year-old man, with rapid onset parkinsonism-dementia complex associated with accumulation of manganese in the brain, secondary to liver failure. A brain MRI was performed and a high signal on T1-weighted images was seen on globus-pallidus, as well as on T2-weighted images on the hemispheric white-matter. He was referred to a liver-transplantation. The patient passed away on the seventh postoperative day. Our findings support the concept of the toxic effects of manganese on the globus-pallidus. The treatment of this form of parkinsonism is controversial and liver-transplantation should not be considered as first line treatment but as an alternative one.

Palavras-chave : manganese; liver transplantation; parkinsonism-dementia; globus pallidus; high-signal.

        · resumo em Português     · texto em Inglês     · Inglês ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons