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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282XOn-line version ISSN 1678-4227

Abstract

BICHUETTI, Denis Bernardi et al. Demyelinating disease in patients with myasthenia gravis. Arq. Neuro-Psiquiatr. [online]. 2008, vol.66, n.1, pp.5-7. ISSN 0004-282X.  http://dx.doi.org/10.1590/S0004-282X2008000100002.

Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.

Keywords : myasthenia gravis; myelinating disease; association.

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