Arquivos de Neuro-Psiquiatria
Print version ISSN 0004-282X
On-line version ISSN 1678-4227
ARAGAO, Maria de Fátima Vasco et al. Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome. Arq. Neuro-Psiquiatr. [online]. 2009, vol.67, n.1, pp.55-57. ISSN 0004-282X. http://dx.doi.org/10.1590/S0004-282X2009000100014.
In two children with near drowning hypoxic encephalopathy and normal-appearing structural MRI, acute proton magnetic resonance spectroscopy (1H MRS) showed biochemical alterations that correctly indicated prognosis and helped to guide management decisions. Elevation of the lipid-lactate and glutamine-glutamate peaks, on the early (72 hour) 1H MRS, predicts a poor prognosis. Absence of lipid-lactate and glutamine-glutamate peaks on the early 1H MRS and reversibility of early mild metabolite abnormalities on follow up examination relates with good outcome.
Keywords : hypoxia; near drowning; magnetic resonance spectroscopy.