SciELO - Scientific Electronic Library Online

vol.69 número1Prenatal exposure to tobacco and alcohol are associated with chronic daily headaches at childhood: A population-based studyPhysical practice is associated with less functional disability in medical students with migraine índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados



Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google


Arquivos de Neuro-Psiquiatria

versión impresa ISSN 0004-282X


PENA, Joaquín A.; RAVELO, María Elena; MORA-LA CRUZ, Eduardo  y  MONTIEL-NAVA, Cecilia. NMO in pediatric patients: brain involvement and clinical expression. Arq. Neuro-Psiquiatr. [online]. 2011, vol.69, n.1, pp. 34-38. ISSN 0004-282X.

OBJECTIVE: To analyze the clinical, neuroimaging characteristics and positivity of the acquaporin water channel (NMO-IgG) in pediatric patients with neuromyelitis optica (NMO). This disorder could have a variable clinical expression. To address such variability, the term NMO spectrum has been suggested. METHOD: We evaluated six pediatric patients, with a median age of 11 years at the time of the study, with the diagnosis of NMO by the Wingerchuck criteria. RESULTS: All the cases exhibited bilateral optic neuritis (ON). Four patients had abnormalities on brain MRI from the onset,although only three of them developed symptoms correlated to those lesions during the course of their disorder. NMO-IgG was positive in 80%. CONCLUSION: Optic neuropathy is the most impaired feature in NMO patients. Brain MRI lesions are not compatible with multiple sclerosis and positivity of the NMO-IgG are also present in NMO pediatric patients, confirming the heterogeneity in the expression of this disorder.

Palabras clave : neuromyelitis optica; multiple sclerosis; optic neuritis; transverse myelitis; pediatric patients.

        · resumen en Español     · texto en Inglés     · Inglés ( pdf epdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons