Abstract

FERNANDES, Maurício et al. Neurological disorders associated with glutamic acid decarboxylase antibodies: a Brazilian series. Arq. Neuro-Psiquiatr. [online]. 2012, vol.70, n.9, pp. 657-661. ISSN 0004-282X.  http://dx.doi.org/10.1590/S0004-282X2012000900002.

Neurological disorders associated with glutamic acid decarboxylase (GAD) antibodies are rare pleomorphic diseases of uncertain cause, of which stiff-person syndrome (SPS) is the best-known. Here, we described nine consecutive cases of neurological disorders associated with anti-GAD, including nine patients with SPS and three cases with cerebellar ataxia. Additionally, four had hypothyroidism, three epilepsy, two diabetes mellitus and two axial myoclonus.

Keywords : glutamic acid decarboxylase antibodies; anti-GAD; neurological disorders; stiff-person syndrome; cerebellar ataxia.