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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282XOn-line version ISSN 1678-4227

Abstract

ABRAHAM, Ronaldo. Steroids in neuroinfection. Arq. Neuro-Psiquiatr. [online]. 2013, vol.71, n.9B, pp.717-721. ISSN 0004-282X.  https://doi.org/10.1590/0004-282X20130158.

The consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumoccocal meningitis is being extended to other forms of Bacterial Meningitis. The same thought can be applied to tuberculous meningitis. In neurocysticercosis and neuroschistosomiasis steroids are more useful than parasiticides in most cases. Despite the evidence favoring the use of steroids in herpes simplex encephalitis, it is not sufficient to definitely support such indication. Among the opportunistic infections that affect AIDS patients, neurotoxoplasmosis and progressive multifocal leukoencephalopaty are those most often considered for the use of steroids; steroids are safe to use, but no definite benefit could be demonstrated in both conditions.

Keywords : steroids; bacterial meningitis; tuberculosis; neuroparasitosis; AIDS; esteróides; meningite bacteriana; tuberculose; neuroparasitoses; AIDS.

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