SciELO - Scientific Electronic Library Online

 
vol.72 issue11Is there correlation between cognition and functionality in severe dementia? The value of a performance-based ecological assessment for Alzheimer’s diseaseDifferential motor alterations in children with three types of attention deficit hyperactivity disorder author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Abstract

SANTIAGO, Michelle Dias Santos et al. Amitriptyline and aerobic exercise or amitriptyline alone in the treatment of chronic migraine: a randomized comparative study. Arq. Neuro-Psiquiatr. [online]. 2014, vol.72, n.11, pp.851-855. ISSN 0004-282X.  http://dx.doi.org/10.1590/0004-282X20140148.

To compare the preventive treatment benefits of amitriptyline and aerobic exercise or amitriptyline alone in patients with chronic migraine.

Method

Sixty patients, both genders, aged between 18 and 50 years, with a diagnosis of chronic migraine, were randomized in groups called amitriptyline and aerobic exercise or amitriptyline alone. The following parameters were evaluated: headache frequency, intensity and duration of headache, days of the analgesic medication use, body mass index (BMI), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) scores.

Results

In the evaluated parameters, was observed decrease in headache frequency (p=0.001), moderate intensity (p=0.048), in headache duration (p=0.001), the body mass index (p=0.001), Beck Depression Inventory (p=0.001) and Beck Anxiety Inventory scores (p=0.001), when groups were compared in the end of third month.

Conclusion

In this study, the amitriptyline was an effective treatment for chronic migraine, but its efficacy was increased when combined with aerobic exercise.

Keywords : chronic migraine; adults; prophylaxis; amitriptyline; aerobic exercise.

        · abstract in Portuguese     · text in English     · English ( pdf )