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Jornal de Pediatria
Print version ISSN 0021-7557
On-line version ISSN 1678-4782
PALHARES, Durval B. and LEME, Lígia M.. A perspective on the control of myositis ossificans progressiva. J. Pediatr. (Rio J.) [online]. 2001, vol.77, n.5, pp.431-434. ISSN 0021-7557. http://dx.doi.org/10.1590/S0021-75572001000500016.
OBJECTIVE: to report four cases of myositis ossificans progressiva, its form of presentation, in addition to new control and treatment options. DESCRIPTION: the authors describe four cases of myositis ossificans progressiva, presenting its clinical manifestations, evolution, and available forms of control and treatment. The main congenital anomalies associated with myosistis ossificans progressiva are described, namely: hallux valgus, clinodactyly, short thumbs, exostosis, and syndactyly. The evolution and therapeutic responses of clinical improvement to oral ascorbic acid and biphosphonate in patients 1 and 4 are also described; patient 1 had a better response after receiving intravenous biphosphonate, while patients 2 and 3 showed clinical improvement after the administration of oral ascorbic acid. COMMENTS: ascorbic acid relieves the pain and improves psychism in patients with myositis ossificans progressiva. Intravenous biphosphonate is an alternative to patients with significant worsening of the disease, especially those with ambulatory restrictions. The orientation towards avoiding recurrent trauma in myositis ossificans progressiva patients is important.
Keywords : myositis ossificans progressiva; ascorbic acid; ectopic ossifications; biphosphonate.