SciELO - Scientific Electronic Library Online

vol.79 número5Clinical and laboratory findings in a series of cases of infective endocarditisClinical and transcutaneous oxygen saturation characteristics in hospitalized infants with acute viral bronchiolitis índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados


Jornal de Pediatria

versión impresa ISSN 0021-7557versión On-line ISSN 1678-4782


AMARAL, Cacyane Naiff do; ALBUQUERQUE, Yael Duarte de; PINTO, Ana Yecê das Neves  y  SOUZA, José Maria de. Importance of clinical and laboratory profiles for the differential diagnosis of malaria and acute viral hepatitis. J. Pediatr. (Rio J.) [online]. 2003, vol.79, n.5, pp.429-434. ISSN 0021-7557.

OBJECTIVE: To establish clinical and diagnostic findings of malaria and acute viral hepatitis in children, stressing similarities and differences, so as to enhance the sensitivity of early malaria diagnosis in childhood. METHODS: Two groups were studied, each including 30 children between 2 and 10 years of age. The patients presented either primary malaria infection or acute viral hepatitis, confirmed by thick blood film and tests for markers of viral hepatitis A and B. The patients were submitted to the following evaluations: erythrocyte, leucocyte and platelet counts, hemoglobin and hematocrit dosage, hepatic enzymes, urea, creatinine and bilirubin dosage. Clinical and laboratory findings were described for both groups and compared. Individuals with alterations on the physical exam in both groups were compared using Fisher's exact test. RESULTS: Baseline clinical findings were the same in all patients: fever, headache, digestive problems and dark urine. One half of malaria patients did not present the classical malaria signs, but all of them presented fever, differently from patients with hepatitis. In malaria patients, anemia and thrombocytopenia were significantly more frequent than in hepatitis patients. A remarkable increase of bilirubin and hepatic enzyme levels was found in hepatitis patients. CONCLUSIONS: A detailed physical examination and a thorough evaluation of non-specific laboratory tests are sufficient to allow the presumptive diagnosis of both malaria and viral hepatitis, and to reinforce the early diagnosis and treatment of malaria.

Palabras clave : Vivax malaria; viral hepatitis; child.

        · resumen en Portugués     · texto en Portugués     · Portugués ( pdf epdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons