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Jornal de Pediatria
On-line version ISSN 1678-4782
PITREZ, Paulo M. C. et al. Rhinovirus and acute bronchiolitis in young infants. J. Pediatr. (Rio J.) [online]. 2005, vol.81, n.5, pp. 417-420. ISSN 1678-4782. http://dx.doi.org/10.2223/JPED.1394.
OBJECTIVE: To determine the prevalence of rhinovirus infection in hospitalized young infants with acute bronchiolitis. METHODS: Hospitalized children with acute bronchiolitis admitted to the Hospital São Lucas/PUCRS between May and September 2002 were selected prospectively. Nasopharyngeal samples were assayed for respiratory syncytial virus, parainfluenza, influenza and adenovirus by immunofluorescence. For rhinovirus test a reverse transcription-polymerase chain reaction for picornavirus was used, followed by hybridization with rhinovirus specific probes. RESULTS: Forty-five patients were selected for the study. The median age of the subjects studied was 2 months. Positive samples for respiratory viruses were found in 35/45 (77.8%) subjects and 7/35 (20%) patients had dual infection. Respiratory syncytial virus was detected in 33/35 (94%) cases. Rhinovirus was detected in 6/35 patients (17%). CONCLUSIONS: Rhinovirus was the second most common agent detected in nasal secretions from young infants hospitalized with acute bronchiolitis.
Keywords : Rhinovirus; respiratory syncytial virus; acute bronchiolitis.