SciELO - Scientific Electronic Library Online

vol.82 issue3Inhaled corticosteroid treatment and growth of asthmatic children seen at outpatient clinicsSerum prevalence of celiac disease in children and adolescents with type 1 diabetes mellitus author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Jornal de Pediatria

Print version ISSN 0021-7557On-line version ISSN 1678-4782


LOPES, Maria Isabella L.; MIRANDA, Paulo J.  and  SARINHO, Emanuel. Use of the skin prick test and specific immunoglobulin E for the diagnosis of cockroach allergy. J. Pediatr. (Rio J.) [online]. 2006, vol.82, n.3, pp.204-209. ISSN 0021-7557.

OBJECTIVE: To compare the prevalence of allergy to cockroaches (Blattella germanica and Periplaneta americana) in asthmatic and non-asthmatic children and to determine the degree of agreement between the skin prick test and serum specific IgE levels, as well as to establish the relationship between cockroach allergy and total IgE levels. METHODS: A case-control study involving 76 asthmatic and 42 non-asthmatic children aged between 6 and 14 years was conducted in Recife, Brazil. All individuals were submitted to the skin prick test and to the measurement of specific IgE for B. germanica and P. americana, as well as to the determination of total IgE concentration. RESULTS: Asthmatic children showed a higher frequency of positive skin reactions to B. germanica (27.6 vs. 4.8%) and P. americana (27.6 vs. 2.4%) than non-asthmatic ones. The agreement between the skin prick test and the specific IgE results was reasonable for B. germanica (kappa = 0.25 ) and weak for P. americana (kappa = 0.17). Those patients who tested positive for cockroaches had a significantly higher geometric mean for total IgE than those who tested negative. The agreement between specific IgE and the skin prick test increased as total IgE levels rose, although some skin tests were negative even when total IgE levels were as high as 5000 kU/l. All determinations of cockroach-specific IgE were positive for total IgE levels greater than 2500 kU/l, even among asymptomatic patients. CONCLUSION: Allergic sensitivity to cockroaches was a predictive factor for asthma severity. The skin prick test is more appropriate for the detection of clinically relevant sensitivity to cockroaches than specific IgE determination.

Keywords : Asthma; cockroaches; hypersensivity.

        · abstract in Portuguese     · text in English | Portuguese     · English ( pdf epdf ) | Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License