SciELO - Scientific Electronic Library Online

 
vol.82 issue5Gastroduodenal peptic ulcer and Helicobacter pylori infection in children and adolescentsPrevalence of symptoms of asthma, rhinitis, and atopic eczema among Brazilian children and adolescents identified by the International Study of Asthma and Allergies in Childhood (ISAAC): phase 3 author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Jornal de Pediatria

Print version ISSN 0021-7557

Abstract

TANAKA, Atsuko; RUGOLO, Ligia M. S. S.; MIRANDA, Antero F. M.  and  TRINDADE, Cleide E. P.. Fractional sodium excretion, urinary osmolality and specific gravity in preterm infants fed with fortified donor human milk. J. Pediatr. (Rio J.) [online]. 2006, vol.82, n.5, pp. 335-340. ISSN 0021-7557.  http://dx.doi.org/10.1590/S0021-75572006000600005.

OBJECTIVE: This research was performed with the objective of investigating the renal effects on premature newborn infants of fortifying banked donor human milk. METHODS: Clinical intervention trial, of the before-and-after type, involving 28 premature newborn infants split into two groups by postconceptional age at the start of the study: GI < 34 weeks (n = 14) and GII > 34 weeks (n = 14), and assessed at three sample points: S1, on unfortified donor human milk, S2, after 3 days, and S3, after 10-13 days on fortified donor human milk. Nutrient intake, weight gain, fractional sodium excretion, urinary osmolality and specific density were compared with two-way ANOVA for repeated measures. RESULTS: Fluids, energy and sodium intakes were similar for both groups, and weight gain was satisfactory. Among the preterms with < 34 weeks postconceptional age, serum sodium was lower at the end of the study and the fractional sodium excretion was elevated at the start and at the end of the study (S1 = 2.11±1.05; S2 = 1.25±0.64; S3 = 1.62±0.88), with a significant difference in relation to GII (S1 = 1.34±0.94; S2 = 0.90±0.54; S3 = 0.91±0.82). Osmolality and urinary specific density were normal, with no differences between groups or collection dates. CONCLUSIONS: No adverse effects on the renal function of these preterms were detected as a result of being fed fortified donor human milk.

Keywords : Human milk; nutritional supplementation; renal function; preterm infants.

        · abstract in Portuguese     · text in English | Portuguese     · pdf in English | Portuguese