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Jornal de Pediatria
On-line version ISSN 1678-4782
KUPEK, Emil and TRITANY, Elaine F.. Impact of vaccination against varicella on the reduction of the disease incidence in children and adolescents from Florianópolis, Brazil. J. Pediatr. (Rio J.) [online]. 2009, vol.85, n.4, pp. 365-368. ISSN 1678-4782. http://dx.doi.org/10.1590/S0021-75572009000400016.
OBJECTIVE: To evaluate the impact of universal early childhood vaccination against varicella on the reduction of its incidence in a state capital in southern Brazil. METHODS: Official epidemiologic surveillance data from the SINAN database for the 1997-2007 period were used to evaluate the impact of varicella vaccination targeting all children < 2 years of age in Florianópolis (the capital city of the state of Santa Catarina), Brazil, since 2002, thus comprising 5 years before and 6 years after the vaccination. Varicella incidence in Florianópolis was compared with the incidence in the rest of the state for four age groups (< 1, 1-4, 5-9, and 10-14 years). RESULTS: Among the 135,311 cases of varicella in the state of Santa Catarina during the 1997-2007 period, 70% were children under 10 years of age. The effectiveness of varicella vaccine ranged from 27 to 38% among the age groups but reached statistical significance only for children 1-4 years old. CONCLUSION: The vaccine was effective in reducing varicella incidence in Florianópolis for children 1-4 years old.
Keywords : Varicella; vaccine; effectiveness.