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Jornal de Pediatria
Print version ISSN 0021-7557
DIMENSTEIN, Roberto et al. Vitamin E in human serum and colostrum under fasting and postprandial conditions. J. Pediatr. (Rio J.) [online]. 2010, vol.86, n.4, pp.345-348. ISSN 0021-7557. http://dx.doi.org/10.1590/S0021-75572010000400016.
OBJECTIVE: To evaluate alpha-tocopherol concentrations in maternal serum and colostrum under fasting and postprandial conditions. METHODS: Thirty healthy childbearing women were recruited in a public maternity hospital, and samples of blood, fasting colostrum, and postprandial colostrum were collected from them up to 12 hours after delivery. RESULTS: The serum alpha-tocopherol concentration was 1,939.8±766.0 μg/dL. Alpha-tocopherol levels in fasting colostrum (1,603.4±911.0 μg/dL) and in postprandial colostrum (1,515.0±890.9 μg/dL) did not demonstrate a statistically significant difference (p > 0.05). There was correlation between alpha-tocopherol levels in fasting and postprandial colostrum (p < 0.05), but not between serum and colostrum. CONCLUSION: The lack of correlation between alpha-tocopherol levels in plasma and in colostrum, and the correlation between alpha-tocopherol concentrations in fasting and postprandial colostrum support the existence of a mechanism that controls the transfer of this nutrient, regardless of dietary intake.
Keywords : Alpha-tocopherol; serum; colostrum.