Effects of soy beverage and soy-based formula on growth, weight, and
               fecal moisture: experimental study in rats

Silva, Maisa de Lima Correia; Speridião, Patrícia da Graça Leite; Marciano, Renata; Amâncio, Olga Maria S.; Morais, Tânia Beninga de; Morais, Mauro Batista de

doi:10.1016/j.jped.2014.09.003

Acessibilidade / Reportar erro

Brasil

Español English

sumário « anterior atual seguinte »

Sumário

Original Articles • J. Pediatr. (Rio J.) 91 (3) • May-Jun 2015 • https://doi.org/10.1016/j.jped.2014.09.003 copy

Effects of soy beverage and soy-based formula on growth, weight, and fecal moisture: experimental study in rats ^☆, ☆ Please cite this article as: Silva MdL, Speridião PdG, Marciano R, Amâncio OM, de Morais TB, de Morais MB. Effects of soy beverage and soy-based formula on growth, weight, and fecal moisture: experimental study in rats. J Pediatr (Rio J). 2015;91:306-12. ^☆☆ ☆☆ Study conducted at Research Laboratory of the Department of Pediatrics, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

Authorship SCIMAGO INSTITUTIONS RANKINGS

OBJECTIVE:

To compare body growth, weight, and fecal moisture in recently weaned rats fed exclusively on infant soy formula and soy-based beverage.

METHODS:

Three similar groups were formed (n = 10/group) consisting of weanling Wistar rats, maintained in metabolic cages. One group was fed soy protein-based beverage, another with soy-based infant formula, and another with cow's milk infant formula (control group). Water and diet were offered ad libitum. Body weight and length were measured. Stool was collected for three consecutive days.

RESULTS:

Weight and length were lower (p = 0.001; p = 0.001) in the groups receiving soy protein-based beverage (73.16 ± 5.74 g; 23.94 ± 1.04 cm) and soy-based formula (71.11 ± 5.84 g; 24.74 ± 0.60 cm) in relation to the group receiving cow's milk formula (84.88 ± 9.75 g; 26.01 ± 0.91 cm). Fresh fecal weight was greater (p < 0.001) in the soy-based beverage (3.44 ± 0.48 g) than in the soy-based formula (0.79 ± 0.20 g) and cow's milk-based formula (0.42 ± 0.17 g). Fecal moisture was higher (p < 0.001) in the group receiving soy protein-based beverage (47.28 ± 9.02%) and soy-based formula (37.21 ± 13.20%) than in the group receiving cow's milk formula (22.71 ± 10.86%).

CONCLUSION:

The growth of rats fed soy protein-based beverage and soy-based formula was lower than those fed cow's milk-based formula. The soy protein-based beverage resulted in significant increase in fecal weight and moisture.

Soy milk; Infant formula; Soy proteins; Milk proteins; Experimental design

Value/100 mL of reconstituted diet	Soy-based beverage	Soy-based infant formula	Cow's milk-based infant formula
Energy (Kcal)^a	42.0	74.1	73.7
Carbohydrate (g)^a	4.7	7.5	8.2
Lipids (g)^a	1.5	4.0	3.9
Protein (g)^a	2.5	2.0	1.5
Sodium (mg)^b	64.0	21.0	17.0
Fiber (g)^b	0	0	0

Variables	Soy-based beverage (N = 8)	Soy-based infant formula (N = 9)	Cow's milk-based infant formula (N = 9)	p
Volume of diet intake (mL)	609.13 ± 56.61	583.56 ± 58.50	538.67 ± 63.61	0.067
Water consumption (mL)	22.50 ± 12.35	20.44 ± 13.41	12.33 ± 6.54	0.154
Consumption of liquid diet + water (mL)	631.63 ± 55.14^a	604.00 ± 64.86^ab	551.00 ± 67.15^b	0.042
Consumption of sodium (mg)	389.84 ± 36.23^a	122.55 ± 12.29^b	91.57 ± 10.81^c	< 0.001
Energy intake (Kcal)	255.83 ± 23.78^b	431.83 ± 43.29^a	398.61 ± 47.07^a	< 0.001
Weight gain (g)	22.34 ± 6.49^a	19.58 ± 6.76^a	32.36 ± 6.00^b	< 0.001
Feed efficiency (g/mL)	0.04 ± 0.01^a	0.03 ± 0.01^a	0.06 ± 0.01^b	< 0.001
Feed efficiency (g/Kcal)	0.09 ± 0.02^a	0.05 ± 0.01^b	0.08 ± 0.01^a	< 0.001

Sociedade Brasileira de Pediatria Av. Carlos Gomes, 328 cj. 304, 90480-000 Porto Alegre RS Brazil, Tel.: +55 51 3328-9520 - Porto Alegre - RS - Brazil
E-mail: jped@jped.com.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] * Corresponding author. E-mails: mbmorais@osite.com.br, maisalcs@yahoo.com.br (M.B. de Morais).