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Hyperuricemia is associated with low cardiorespiratory fitness levels and excess weight in schoolchildren Please cite this article as: Reis LN, Renner JD, Reuter CP, Horta JA, Paiva DN, Valim AR, et al. Hyperuricemia is associated with low cardiorespiratory fitness levels and excess weight in schoolchildren. J Pediatr (Rio J). 2017;93:538–43. ,☆☆ ☆☆ Study carried out at Universidade de Santa Cruz do Sul (UNISC), Santa Cruz do Sul, RS, Brazil.

Abstract

Objective:

To evaluate the possible association between hyperuricemia and cardiorespiratory fitness levels/nutritional profile, grouped into a single variable, in schoolchildren.

Method:

Cross-sectional study of 2335 students from Elementary schools, aged 7–17 years of both genders, stratified by conglomerates of a municipality in Southern Brazil. Body mass index (BMI) was calculated and cardiorespiratory fitness (CRF) was assessed by the 6-minute run/walk test. The BMI and CRF were grouped into a single variable, considering: (1) low and normal weight/fit; (2) low and normal weight/unfit; (3) overweight-obesity/fit; (4) overweight-obesity/unfit. The Poisson regression (prevalence ratio, PR) was used for the association between hyperuricemia and BMI/CRF ratio with 95% confidence intervals and differences were considered significant when p < 0.05.

Results:

There is an association, although subtle, between the presence of hyperuricemia with low levels of CRF and the presence of excess weight, when grouped into a single variable. Boys and girls with this condition have higher prevalence of hyperuricemia (PR: 1.07; p = 0.007 for boys; PR: 1.10; p < 0.001 for girls).

Conclusion:

Together, excess weight and low levels of cardiorespiratory fitness are associated with the presence of hyperuricemia in schoolchildren.

KEYWORDS
Hyperuricemia; Physical fitness; Overweight; Child; Adolescent

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