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vol.53 issue3Processed electroencephalogram in children anesthetized with sevoflurane. Is it feasible?Comparative study of 0.5% bupivacaine versus 0.5% bupivacaine enantiomeric mixture (S75-R25) in epidural anesthesia for orthopedic surgery author indexsubject indexarticles search
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Revista Brasileira de Anestesiologia

Print version ISSN 0034-7094On-line version ISSN 1806-907X


IMBELLONI, Luiz Eduardo et al. Spinal anesthesia for cesarean section with 0.5% isobaric bupivacaine plus fentanyl and morphine: prospective study with different volumes. Rev. Bras. Anestesiol. [online]. 2003, vol.53, n.3, pp.322-330. ISSN 0034-7094.

BACKGROUND AND OBJECTIVES: Spinal block for cesarean section was described few years after the first report of spinal anesthesia by Bier in 1899. It was not until the last 5 years that spinal anesthesia has become the most frequent anesthetic method for cesarean section at our hospital. This prospective study aimed at evaluating 0.5% spinal isobaric bupivacaine for cesarean section, injected after fentanyl and morphine, in the lateral position, and at correlating the incidence of hemodynamic changes and cephalad spread with different volumes. METHODS: Participated in this study 100 patients undergoing spinal anesthesia for elective cesarean delivery who were randomly allocated into three groups to receive: 4 ml (20 mg), 3 ml (15 mg) or 2.5 ml (12.5 mg) of 0.5% isobaric bupivacaine after 25 µg fentanyl plus 50 µg morphine. The following parameters were evaluated and compared: analgesia and motor block onset, cephalad spread of analgesia, cardiovascular changes and the incidence of nausea and vomiting. RESULTS: The three volumes of 0.5% isobaric bupivacaine produced comparable effects. Onset was longer for the lowest dose. There were no differences in cephalad spread, number of patients with high cervical levels, cardiovascular changes and post dural puncture headache. Maximum analgesic level was T4 (range: T3-T6) with 4 ml, T4 (range: T4-T11) with 3 ml and T4 (range: T4-T8) with 2.5 ml. No patient required ephedrine to treat arterial hypotension. Motor block was incomplete for all patients. One patient developed post dural puncture headache. CONCLUSIONS: Results of this study confirm that 0.5% isobaric bupivacaine, following fentanyl and morphine injected with separate syringes and in the lateral position, in doses of 2.5, 3 and 4 ml provides a fast and effective anesthesia for cesarean section.

Keywords : ANALGESICS [Opioids]; ANALGESICS [fentanyl]; ANALGESICS [morphine]; ANESTHETICS [Local]; ANESTHETICS [bupivacaine]; ANESTHETIC TECHNIQUES [Regional]; ANESTHETIC TECHNIQUES [spinal block]; SURGERY [Obstetric]; SURGERY [cesarean section].

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