SciELO - Scientific Electronic Library Online

vol.53 issue4Xenon: pharmacology and clinical use author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista Brasileira de Anestesiologia

Print version ISSN 0034-7094On-line version ISSN 1806-907X


TANAKA, Pedro Paulo  and  TANAKA, Maria Aparecida Almeida. Hemoglobin-based blood substitutes: current status and perspectives. Rev. Bras. Anestesiol. [online]. 2003, vol.53, n.4, pp.543-554. ISSN 0034-7094.

BACKGROUND AND OBJECTIVES: Alternatives to red blood cells transfusion have been studied since the fifties. This study aimed at presenting current status and perspectives of hemoglobin-based blood substitutes. CONTENTS: Potential application areas are presented, in addition to clinical studies involving major hemoglobin molecules developed, their advantages and limitations. CONCLUSIONS: Several randomized trials have shown efficacy in avoiding or decreasing red blood cells transfusions, however there are some limitations and the future blood substitute shall at least have the same safety and efficacy of blood itself.

Keywords : BLOOD [artificial oxygen carriers].

        · abstract in Portuguese | Spanish     · text in Portuguese     · Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License